1.D.39 The Light-controlled Azobenzene-based Amphiphilic Molecular Ion Channel (AAM-IC) Family

Light-regulated ion channel-mediated transport across lipid bilayers has been realized using structurally simple azobenzene-based amphiphilic small molecules. UV or visible irradiation triggers molecular photoisomerization, which induces structural and membrane affinity changes in self-assembled channels. This results in light-regulated ion transmembrane transport (Liu et al. 2013).

References:

Liu, T., C. Bao, H. Wang, Y. Lin, H. Jia, and L. Zhu. (2013). Light-controlled ion channels formed by amphiphilic small molecules regulate ion conduction via cis-trans photoisomerization. Chem Commun (Camb) 49: 10311-10313.