1.E.6 The T7 Holin (T7 Holin) Family See 1.E for a generalized description of Holins.
This family belongs to the Holin II Superfamily .
References:
Lee, J.S., H.B. Jang, K.S. Kim, T.H. Kim, S.P. Im, S.W. Kim, J.M. Lazarte, J.S. Kim, and T.S. Jung. (2015). Complete Genomic and Lysis-Cassette Characterization of the Novel Phage, KBNP1315, which Infects Avian Pathogenic Escherichia coli (APEC). PLoS One 10: e0142504.
Nguyen, H.M. and C. Kang. (2014). Lysis Delay and Burst Shrinkage of Coliphage T7 by Deletion of Terminator T{varphi} Reversed by Deletion of Early Genes. J. Virol. 88: 2107-2115.
Summer, E.J., C.J. Enderle, S.J. Ahern, J.J. Gill, C.P. Torres, D.N. Appel, M.C. Black, R. Young, and C.F. Gonzalez. (2010). Genomic and biological analysis of phage Xfas53 and related prophages of Xylella fastidiosa. J. Bacteriol. 192: 179-190.
Xu, Y., Y. Ma, S. Yao, Z. Jiang, J. Pei, and C. Cheng. (2015). Characterization, Genome Sequence, and Analysis of Escherichia Phage CICC 80001, a Bacteriophage Infecting an Efficient L-Aspartic Acid Producing Escherichia coli. Food Environ Virol. [Epub: Ahead of Print]
Examples:
TC#	Name	Organismal Type	Example
1.E.6.1.1	*17.5 lysis protein, gb17.5 (67 aas); the phage T7 holin (Nguyen and Kang 2014). This holin is 94% identical to the holin from E. coli* phage CICC 80001 (Xu et al. 2015).**	Proteobacterial phage T7	*gb17.5 of E. coli* phage T7**

1.E.6.1.2	Putative lysis protein	Vibriophage	*Putative lysis protein of Vibrio* phage ICP3**

1.E.6.1.3	Type II holin	Proteobacterial phage	*Type II holin of Pseudomonas* phage gh-1**

Examples:
TC#	Name	Organismal Type	Example
1.E.6.2.1	Putative holin	Proteobacterial viruses	*Putative holin of Caulobacter* phage Cd1**

1.E.6.2.2	Putative holin-like phage protein	Proteobacteria	Putative holin-like phage protein of Candidatus Glomeribacter gigasporarum

1.E.6.2.3	Hypothetical protein	Proteobacteria	Hypothetical protein of Comamonas testosteroni

1.E.6.2.4	Putative class II holin	Proteobacterial phage	Class II holin of Enterbacterial phage LKA1

1.E.6.2.5	Holin of 77 aas and 1 central TMS from E. coli phage ECBP5, Orf46. This protein is nearly identical to the pin-holin characterized for E. coli phage KBNP1315 (Lee et al. 2015). It infects a pathogenic avian E. coli strain (Lee et al. 2015).		Holin of phage ICBP5 or KBNP1315.

1.E.6.2.6	Putative holin of 60 aas and 1 TMS		Holin of Pectobacterium phage PP1

1.E.6.2.7	Putative holin of 64 aas and 1 TMS		Holin of Lysobacter dokdonensis

1.E.6.2.8	Putative holin of 107 aas and 2 TMSs.		Holin of Stenotrophomonas maltophilia

1.E.6.2.9	Holin of 62 aas		*Holin of Ralstonia* phage RsoP1IDN**

Examples:
TC#	Name	Organismal Type	Example
1.E.6.3.1	*Phage pinholin (Summer et al.* 2010).**	Proteobacterial phage	*Pinholin of Xyella* phage Xfas53**

1.E.6.3.2	putative pinholin	Proteobacteria	Pinholin of Stenophomonas maltophilia

1.E.6.3.3	Putatuve pinholin	Proteobacteria	Pinholin of Delftia acidovorans

1.E.6.3.4	Putative pinholin	Proteobacteria	Pinholin of Comamonas testosteroni

1.E.6.3.5	Putative pinholin	Proteobacteria	Pinholin of Laribacter honkongensis

1.E.6.3.6	Holin of 61 aas and 1 C-terminal TMS.		*Holin of Vibrio* phage vB_ValA_R15Z.**