1.M.5. The Putative Spanin5 (Spanin5) Family

This family initially consisted of a single pair of proteins, both designated 'spanin' in the NCBI and UniProt databases, and both having an N-terminal TMS. They are from Burkholderia phage BcepF1 and are encoded by adjacent genes. More homoogues have since been discovered, and some are included in TCDB. They probably all consist of two proteins, one about 100 - 110 aas long, and the other of about 60 aas, also with one N-terminal TMS.

Examples:

TC#

Name

Organismal Type

Example

1.M.5.1.1

Two component putative spanin of 103 and 57 aas, respectively.

Spanin of Burkholderia phage BcepF1

1.M.5.1.2

i-spanin/o-spanin of 104 and 57 aas, respectively, each with one N-terminal TMS.

Spanin of Burkholderia phage Maja

1.M.5.1.3

Spanin of 116 aas and 1 N-terminal TMS with two additional potential weakly hydrophobic TMSs.

Spanin of Myoviridae sp.

1.M.5.1.4

Spanin of 104 aas and 1 N-terminal TMS + 2 weakly hydrophobic putative TMSs.

Spanin of Burkholderia phage BCSR52