1.S.9.  The Bacterial/Archaeal Nanocompartment Encapsulin Shell Protein4 (BANC-SP4) Family

The BANC-SP4 family is represented by the encapsulin, EncD. It is a cargo protein of a type 1 encapsulin nanocompartment. It may help nucleate Fe atoms in the interior of the encapsulin nanocompartment and is present in about 47 copies/encapsulin nanocompartment (McHugh et al. 2014).


 

References:

McHugh, C.A., J. Fontana, D. Nemecek, N. Cheng, A.A. Aksyuk, J.B. Heymann, D.C. Winkler, A.S. Lam, J.S. Wall, A.C. Steven, and E. Hoiczyk. (2014). A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress. EMBO. J. 33: 1896-1911.

Sigmund, F., S. Pettinger, M. Kube, F. Schneider, M. Schifferer, S. Schneider, M.V. Efremova, J. Pujol-Martí, M. Aichler, A. Walch, T. Misgeld, H. Dietz, and G.G. Westmeyer. (2019). Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters. ACS Nano 13: 8114-8123.

Examples:

TC#NameOrganismal TypeExample
1.S.9.1.1

EncD is a cargo protein of a type 1 encapsulin nanocompartment. It may help nucleate Fe atoms in the interior of the encapsulin nanocompartment. and is present in about 47 copies/encapsulin nanocompartment (McHugh et al. 2014). The encapsulin and a cargo construct (an encB-encC-encD fusion) can be overexpressed in E. coli and in human HEK293T cells. In HEK293T in the presence of 0.5 M ferrous ammonium sulfate (Sigmund et al. 2019).

EncD of Myxococcus xanthus

 
1.S.9.1.2

Uncharacterized protein of 112 aas

UP of Thermococcus kodakarensis

 
1.S.9.1.3

Uncharacterized protein of 90 aas.

UP of Pyxidicoccus fallax

 
Examples:

TC#NameOrganismal TypeExample
1.S.9.2.1

Uncharacterized protein of 309 aas.

UP of Aureococcus anophagefferens (Harmful bloom alga)