2.A.98 The Putative Sulfate Exporter (PSE) Family

Many putative 10 or 11 TMS bacterial proteins comprise the PSE family. They are found in diverse bacteria and archaea. The genes encoding some of these homologues may be induced by growth in the presence of cysteate (suyZ) or taurine (tauZ) (COG2855; Rein et al., 2005). These proteins are related to the 12 TMS members of the CPA superfamily and are distantly related to the MadML malonate:H+ symporter (TC #2.A.70).


This family belongs to the CPA Superfamily.
 

References:

Bruggemann, C., K. Denger, A.M. Cook, and J. Ruff. (2004). Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans. Microbiology 150: 805-816.
Rein, U., R. Gueta, K. Denger, J. Ruff, K. Hollemeyer, and A.M. Cook. (2005). Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA. Microbiology 151: 737-747.
Examples:

TC#NameOrganismal TypeExample
2.A.98.1.1Cysteate-inducible putative sulfate efflux pump, SuyZ (Rein et al., 2005).BacteriaSuyZ of Paracoccus pantotrophus (AAS78796)
 
2.A.98.1.2Taurine-inducible putative sulfate exporter, TauZ (Rein et al., 2005)BacteriaTauZ of Paracoccus denitrificans (Q6RH59; 338 aas)
 
2.A.98.1.3YeiH putative efflux pumpBacteriaYeiH of E. coli (NP_416663)
 
2.A.98.1.4

Membrane Protein (339 aas; 11 putative TMSs) (gives e-7 with MadM (2.A.70.1.1 in a TC Blast search).

Bacteria

Membrane protein of Streptococcus porcinus (F3LB58)

 
2.A.98.1.5

Uncharacterized protein of 355 aas and 8 TMSs.

UP of Polysphondylium pallidum

 
2.A.98.1.6

Uncharacterized protein of 538 aas and 13 TMSs.

UP of Mucor circinelloides (Mucormycosis agent) (Calyptromyces circinelloides)

 
2.A.98.1.7

Uncharacterized protein of 480 aas and 12 TMSs in a 4 + 4 + 4 arrangement.

UP of Desulfovibrio desulfuricans

 
Examples:

TC#NameOrganismal TypeExample
2.A.98.2.1Conserved hypothetical protein with 10 putative TMSs

Archaea

ORF of Archaeoglobus fulgidus (O28652)

 
Examples:

TC#NameOrganismal TypeExample
2.A.98.3.1

Uncharacterized DUF819 domain-containing protein of 419 aas and 11 TMSs.

UP of Flavobacterium gillisiae

 
2.A.98.3.2

DUF819 domain-containing proteinof 387 aas and 11 TMSs.

DUF819 protein of Facklamia miroungae

 
2.A.98.3.3

DUF819 family protein of 407 aas and 12 TMSs in a 6 + 6 TMS arrangement.

DUF819 protein of Scopulibacillus daqui

 
2.A.98.3.4

DUF819 protein of 602 aas and 11 or 12 TMSs in a 3 + 3 or 4 +2 + 2 + 1 TMS arrangement.

DUF819 protein of Toxoplasma gondii
 
2.A.98.3.5

Uncharacterized protein of 605 aas and 12 TMSs in a 3 + 4 + 2 + 2 + 1 TMS arrangement.

UP of Besnoitia besnoiti

 
2.A.98.3.6

Uncharacterized protein of 522 aas and 12 TMSs in a 6 + 6 TMS arrangement.

UP of Plasmodium falciparum