8.B.38.  The Conotoxin J (CTx J) Family

This family consists of conotoxins of about 60 - 80 aas with one or sometimes two putative TMSs.


 

References:

Imperial, J.S., P.S. Bansal, P.F. Alewood, N.L. Daly, D.J. Craik, A. Sporning, H. Terlau, E. López-Vera, P.K. Bandyopadhyay, and B.M. Olivera. (2006). A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry 45: 8331-8340.
Examples:

TC#NameOrganismal TypeExample
8.B.38.1.1

Conotoxin Bu28 of 76 aas and 1 or 2 TMSs.

CTx Bu28 of Conus bullatus (Bubble cone)

 
8.B.38.1.2

α/κ-conotoxin-like fe14.1 of 76 aas and 1 or 2 TMSs. It is an inhibitor of Kv1.6 channel and nAChR subtypes (Imperial et al. 2006).

CoTx of Conus ferrugineus