9.B.126 The Putative Lipid IV Exporter (YhjD) Family

The YhjD family is also called the virulence facter BrkB family (Mamat et al. 2008). It is distantly related to the YihY family, and hence YihY is included in this family (TC# 9.B.126.2.1). The earlier postulate that homologues are a ribonuclease RN proved to be incorrect. 


 

References:

Mamat, U., T.C. Meredith, P. Aggarwal, A. Kühl, P. Kirchhoff, B. Lindner, A. Hanuszkiewicz, J. Sun, O. Holst, and R.W. Woodard. (2008). Single amino acid substitutions in either YhjD or MsbA confer viability to 3-deoxy-d-manno-oct-2-ulosonic acid-depleted Escherichia coli. Mol. Microbiol. 67: 633-648.

Examples:

TC#NameOrganismal TypeExample
9.B.126.1.1

Putative lipid exporter, YhjD; suppressor of MsbA and KDO essentiality. (337aas; 6 TMSs) (Mamat et al., 2008).

Bacteria

YhjD of E. coli (P37642)

 
9.B.126.1.2

Virulence factor, BrkB, essential for resistance to complement-dependent killing by serum.

Bacteria

BrkB of Bifidobacterium longum (I3AVH2)

 
9.B.126.1.3

Uncharacterized protein of 401 aas and 6 or 7 TMSs.

UP of Microbacterium maritypicum

 
9.B.126.1.4

Uncharacterized protein of 341 aas and 7 TMSs.

UP of Rhodococcus equi (Corynebacterium equi)

 
9.B.126.1.5

Uncharacterized protein of 341 aas and 6 TMSs.

UP of Kitasatospora setae (Streptomyces setae)

 
Examples:

TC#NameOrganismal TypeExample
9.B.126.2.1

Predicted inner membrane protein; YihY

Bacteria

YihY of E. coli (P0A8K8)

 
9.B.126.2.2

6 TMS protein of 396 aas; virulence factor of the BrkB family.

Fusobacteria

Membrane protein of Fusobacterium nucleatum

 
9.B.126.2.3

Uncharacterized protein of 794 aas

Spirochaetes

UP of Leptospira interrogans

 
9.B.126.2.4

uncharacterized protein of 304 aas and 6 TMSs

Proteobacteria

UP of Maricaulis maris

 
9.B.126.2.5

Uncharacterized YihY family protein of 299 aas and 7 TMSs

Firmicutes

YihY family protein of Lactobacillus fermentum

 
9.B.126.2.6

Uncharacterized protein of 306 aas and 6 TMSs

UP of Cyanothece sp. (strain PCC 7425)

 
9.B.126.2.7

Uncharacterized protein of 284 aas and 6 TMSs

UP of Firmicutes bacterium CAG:114

 
9.B.126.2.8

Uncharacterized protein of 265 aas and 6 TMSs.

UP of Thermus thermophilus

 
9.B.126.2.9

Uncharacterized protein of 363 aas and 6 TMSs.

UP of Arthrobacter agilis

 
Examples:

TC#NameOrganismal TypeExample
Examples:

TC#NameOrganismal TypeExample