9.B.330.  The DUF4013 (DUF4013) Family 

These proteins appear to occur as single proteins encoded by genes adjacent to genes of unrelated apparent functions, but sometimes they are adjacent to another membrane protein of similar seqence.     In several systems examined, ABC-type ATPases do not appear to occur within the same operon. These proteins are found in Archaea and Bacteria. They can have from 4 to 6 TMSs, and sometimes have hydrophilic extensions. The proteins with TC# 9.B.330.4.X are annotated as prolipoprotein diacylglyceryl transferases as are some of their homologues in NCBI.


Examples:

TC#NameOrganismal TypeExample
9.B.330.1.1

Uncharacterized protein of 371 aas and 6 TMSs

UP of Halorubrum kocurii

 
9.B.330.1.2

Putative transporter of unknown function.  Two genes of similar sequence appear to occur adjacent to each other.  These may together comprise a transport system.

Putative 2 component transporter of an archaeon, AarcLI
AUX07852, a protein of 218 aas and 5 putative TMSs.
AUXo7853, a protein of 336 aas and 6 putative TMSs.

 
9.B.330.1.3

Putative 2 component transporter of unknown function

Putative transporter of Chloroflexi bacterium
HBX69530, protein of 230 and 5 TMSs
HBX69529, protein of 227 aas and 4 TM

 
9.B.330.1.4

DUF4013 domain-containing protein of 212 aas and 5 TMSs.

DUF4013 protein of Methanoplanus limicola

 
9.B.330.1.5

DUF4013 domain-containing protein of 364 aas and 5 C-terminal TMSs.

DUF4013 protein of Natrinema altunense

 
9.B.330.1.6

Uncharacterized protein of 202 aas and 5 TMSs in a 1 + 2 + 2 arrangement.

UP of Opitutae bacterium

 
9.B.330.1.7

DUF4013 domain-containing protein of 212 aas and 5 TMSs in a 1 + 2 + 2 arrangement.

DUF4013 protein of Methanococcus maripaludis

 
9.B.330.1.8

DUF4013 domain-containing protein of 222 aas and 5 TMSs in a 1 + 2 + 2 TMS arrangement.

DUF4013 domain protein of Sphaerobacteraceae bacterium

 
Examples:

TC#NameOrganismal TypeExample
9.B.330.2.1

DUF4013 protein of 285 aas and 5 or 6 TMSs

DUF4013 protein of Senegalimassilia sp.

 
9.B.330.2.2

DUF4013 domain-containing protein of 340 aas and 5 TMSs.

DUF4013 protein of Olsenella umbonata

 
9.B.330.2.3

Uncharacterized DUF4013 domain-containing protein of 273 aas and 6 TMSs in a 1 + 2 + 2 + 1 arrangement.

DUF4013 protein of Asaccharobacter celatus

 
Examples:

TC#NameOrganismal TypeExample
9.B.330.3.1

Uncharacterized protein of 253 aas and 6 TMSs.

UP of Candidatus Rokubacteria bacterium (soil metagenome)

 
9.B.330.3.2

Uncharacterized protein of 289 aas and 5 TMSs.

UP of Planctomycetes bacterium

 
Examples:

TC#NameOrganismal TypeExample
9.B.330.4.1

Prolipoprotein diacylglyceryl transferase of 303 aas and 7 TMSs in a 1 + 1 + 2 + 2 + 1 arrangement.

Transferase of Devosia crocina

 
9.B.330.4.2

Prolipoprotein diacylglyceryl transferase of 272 aas and 7 TMSs in a 2 + 2 + 3 TMS arrangement.

Transferase of Lactobacilus plantarum

 
9.B.330.4.3

Prolipoprotein diacylglyceryl transferase 2, phosphatidylglycerol:prolipoprotein diacylglycerol transferase, Lgt, of 285 aas and 3 TMSs, one N-terminal and two C-terminal.

Lgt of Candidatus Beckwithbacteria bacterium

 
9.B.330.4.4

Prolipoprotein diacylglyceryl transferase of 260 aas and 7 TMSs.

DAGT of Candidatus Peribacter riflensis