9.B.371.  The PaaI Thioesterase (PTE) Family 

These proteins are small (usually around 130 - 200 aas in length with 0 - 3 putative TMSs.  They are annotated either as PaaI thioesterases or hydroxyphenylacetyl-CoA thioesterases or acyl-CoA thioesterases or hotdog-fold thioesterases. These proteins, listed as a subfamily with TC# 9.B.371.1, are distantly related to another subfamily with TC# 9.B.371.2.



This family belongs to the Hydrolase Superfamily.

Examples:

TC#NameOrganismal TypeExample
9.B.371.1.1

Putative PaaI family thioesterase of 141 aas and 1 - 3 TM

PaaI family protein of Ruminiclostridium hungatei

 
9.B.371.1.2

PaaI family thioesterase of 158 aas and 3 TMSs.

Thioesterase of Streptomyces sp. BPSDS2

 
9.B.371.1.3

Uncharacterized protein of 169 aas and up to 4 TMSs.

UP of Exophiala aquamarina

 
9.B.371.1.4

Hotdog fold thioesterase of 134 aas and possibly up to 3 TM

thioesterase of Flavobacterium magnum

 
9.B.371.1.5

PaaI family thioesterase of 131 aas and possibly 3 TMSs.

Esterase of Mameliella alba

 
9.B.371.1.6

PaaI family thioesterase of 173 aas and 3 - 5 TMSs.

PaaI thioesterase of Streptomyces malaysiensis

 
9.B.371.1.7

Hotdog fold thioesterase of 164 as and 1 TM

Thioesterase of Qipengyuania sp. GH38

 
9.B.371.1.8

YigI of 155 aas and 2 or 3 TMSs, one N-terminal, one central, and possibly one C-terminal. This protein is in the thioesterase family, resembles other members of this family, and may therefore be one. 

YigI of E. coli

 
Examples:

TC#NameOrganismal TypeExample
9.B.371.2.1Peroxisomal Acyl-CoA thioesterase-12, Acot12 (2-4 putative TMSs)AnimalsAcot12 of Homo sapiens (Q8WYK0)
 
9.B.371.2.2

Acyl-CoA thioesterase of 342 aa

Thioesterase of Kocuria palustris

 
9.B.371.2.3

Acyl-coenzyme A thioesterase 9, mitochondrial-like of 592 aas.

Thioesterase of Quercus suber

 
9.B.371.2.4

Acyl-CoA thioesterase of 166 aas.

Thioesterase of Serpentinicella alkaliphila

 
9.B.371.2.5

Acyl-CoA thioesterase of 137 aa

Thioesterase of Pseudomonas mendocina

 
9.B.371.2.6

Acyl-CoA thioesterase of 145 aa

Thioesterase of Meiothermus terrae

 
Examples:

TC#NameOrganismal TypeExample