9.B.56 The Bacterial Disease Resistance and Oomycete Disease Susceptibility Protein, PIMP1 (PIMP1) Family These proteins are required for defense responses to Xanthomonas campestris pv. vesicatoria (Xcv). In heterologous systems, they confers resistance to bacterial pathogens such as Pseudomonas syringae pv. tomato but susceptibility to pathogenic oomycetes such as Hylaloperonospora parasitica when expressed in Arabidopsis thaliana or Capsicum annuum (Bell pepper) (Hong et al. 2008). May be involved in the regulation of responses to bitoic and abiotic stresses (Hong and Hwang 2009). These proteins belong to the DUF588 or MARVEL superfamily. MARVEL domain-containing proteins are often found in lipid-associating proteins such as Occludin and MAL family proteins.
References:
Hong, J.K. and B.K. Hwang. (2009). The promoter of the pepper pathogen-induced membrane protein gene CaPIMP1 mediates environmental stress responses in plants. Planta 229: 249-259.
Hong, J.K., D.S. Choi, S.H. Kim, S.Y. Yi, Y.J. Kim, and B.K. Hwang. (2008). Distinct roles of the pepper pathogen-induced membrane protein gene CaPIMP1 in bacterial disease resistance and oomycete disease susceptibility. Planta 228: 485-497.
Examples:
TC#	Name	Organismal Type	Example
9.B.56.1.1	*The 4 TMS CASP-like protein of 166 aas, PIMP1 (Hong et al.* 2008).**		*PIMP1 of Capsicum annuum* (Bell pepper)**

9.B.56.1.10	CASP-like protein of 143 aas and 3 or 4 TMSs		*CASP-like protein of Oryza sativa* subsp. indica (Rice)**

9.B.56.1.2	CASP (DUF588; MARVEL superfamily) domain protein of 188 aas and 4 TMSs		*PIMP1 of Arabidopsis thaliana* (Mouse-ear cress)**

9.B.56.1.3	CASP-like protein 4A1 of 306 aas with an N-terminal pollen-specific leucine-rich repeat sequence and 4 C-terminal TMSs.		*Protein 4A1 of Zea mays* (Maize)**

9.B.56.1.4	CASP-like protein of 207 aas and 4 TMSs		CASP-like protein of Brassica rapa (Chinese cabbage) (Brassica pekinensis)

9.B.56.1.5	CASP-like protein 1D2 of 199 aas and 4 TMSs.		*Protein 1D2 of Arabidopsis thaliana* (Mouse-ear cress)**

9.B.56.1.6	CASP-like protein of 208 aas and 4 TMSs		CASP-like protein of Glycine max (Soybean) (Glycine hispida)

9.B.56.1.7	CASP-like protein VIT of 178 aas and 4 TMSs.		*VIT of Solanum tuberosum* (Potato)**

9.B.56.1.8	CASP-like (MtN24-like) protein of 296 aas and 4 TMSs		*CASP-like protein of Phaseolus vulgaris* (Kidney bean) (French bean)**

9.B.56.1.9	CASP-like protein of 152 aas and 4 TMSs		CASP-like protein of Prunus persica (Peach) (Amygdalus persica)

Examples:
TC#	Name	Organismal Type	Example
9.B.56.2.1	Uncharacterized MARVEL-domain membrane protein of 169 aas and 4 TMSs		UP of Gibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium fujikuroi)

9.B.56.2.2	Membrane protein of 173 aas and 4 TMSs.		UP of Metarhizium robertsii (Metarhizium anisopliae

9.B.56.2.3	Uncharacterized protein of 178 aas and 4 TMSs		UP of Fusarium oxysporum

9.B.56.2.4	Uncharacterized protein of 558 aas and 5 N-terminal TMSs plus a C-terminal DUF3712 domain.		UP of Ajellomyces dermatitidis (Blastomyces dermatitidis)