3.A.9.1.4
The 20 component Ycf2-FtsHi chloroplast protein import motor complex:
The Ycf2-FtsHi complex functions as a
TIC complex-associated ATPase motor in
chloroplast protein import. Cryo-EM
structure of the native Chlamydomonas reinhardtii Ycf2-FtsHi complex revealed up to 19 or 20
subunits, including conserved
heterohexameric motor components and
multiple green-algae-specific
components (). This offers evolutionary
insights into the conservation and
diversity of the chloroplast import motor
across species.
- •
Structure of the Chlamydomonas Ycf2-FtsHi complex revealed its composition and assembly.
- •
ATP binding induces a conformational changes in the ATPase domain of Ctap1.
- •
The preprotein interacts with Ycf2-FtsHi and enhances its ATPase activity in vitro.
- •
Ycf2-FtsHi exhibits evolutionary diversity between green algae and land plants,
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| Accession Number: | 8XQX_H |
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| Protein Name: | H Chain H, PcyA |
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| Length: | 556 |
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| Molecular Weight: | |
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| Species: | Chlamydomonas reinhardtii [3055] |
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| Number of TMSs: | 1 |
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| Substrate |
protein |
|---|
1: MMSSIPKSIG AQRSAASTRA HALARPVVLA PAASIPARSQ GVTSTSGRCL APPPRAAAGA
61: GAPGTAGPTN AGAAAHEVEV DAVESPLSPE DIMRLVQQHE DVAAAAESEQ LVAQFRDDPQ
121: GLYEYVNRAY AEGPRRVTTP ISLLQEEITG AVTESYPAAV ANDIIGMGSW RLKDDVDPVI
181: EFLVARLEGC WREILDTDLC LYPREKWKEQ GWDLVDSMDP HQELEGFSYA DIPDPAKGEA
241: GYPRLQLENR VYCSKVFRKL HVEVGLRQDG LQVLHVVVYP RYSYDMPIFG MDIVMVDGRV
301: TLAVVDCCPV RADLKLQPHY METMALLQRT FLEGTDPALR RIPEWGSKIF SPLALCITPS
361: GPEELAAFAK YAVALHRAYL TMSLNAVPVV AGPGDRREAA RLQEIQDGQK RFCDNQLVNK
421: KTRRVLEVAM GVEWTEAYMS QLMFDFDPKY EPPYFDASFE KLYTYFDENP SFGEMADEAM
481: ELERGAEAER ANETMAAALS GRSVSREKLA MAMGFLFQND ATFRAAVQTL SGGQVDGNIE
541: ERLTDDLMQL LERSE