1.X.1.1.1
The Intraflagellar transporter (IFT) multiprotein complex. WD repeat-containing protein 35 of 1181 aas and possibly as many as 7 or 8 TMSs. It is a component of the IFT complex A (IFT-A), a complex required for
retrograde ciliary transport and entry into cilia of G protein-coupled
receptors (GPCRs). It is thus involved in ciliogenesis and ciliary protein
trafficking (Takahara et al. 2018) (see the family description). Many other proteins play a role as constituents of the IFT complex, and some of these (but not all of them) are listed under this TC# (Lechtreck 2022).
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| Accession Number: | A0AVF1 |
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| Protein Name: | Intraflagellar transport protein 56 |
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| Length: | 554 |
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| Molecular Weight: | 64178.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Cell projection1 |
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| Substrate |
protein |
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1: MMLSRAKPAV GRGVQHTDKR KKKGRKIPKL EELLSKRDFT GAITLLEFKR HVGEEEEDTN
61: LWIGYCAFHL GDYKRALEEY ENATKEENCN SEVWVNLACT YFFLGMYKQA EAAGFKASKS
121: RLQNRLLFHL AHKFNDEKKL MSFHQNLQDV TEDQLSLASI HYMRSHYQEA IDIYKRILLD
181: NREYLALNVY VALCYYKLDY YDVSQEVLAV YLQQIPDSTI ALNLKACNHF RLYNGRAAEA
241: ELKSLMDNAS SSFEFAKELI RHNLVVFRGG EGALQVLPPL VDVIPEARLN LVIYYLRQDD
301: VQEAYNLIKD LEPTTPQEYI LKGVVNAALG QEMGSRDHMK IAQQFFQLVG GSASECDTIP
361: GRQCMASCFF LLKQFDDVLI YLNSFKSYFY NDDIFNFNYA QAKAATGNTS EGEEAFLLIQ
421: SEKMKNDYIY LSWLARCYIM NKKPRLAWEL YLKMETSGES FSLLQLIAND CYKMGQFYYS
481: AKAFDVLERL DPNPEYWEGK RGACVGIFQM IIAGREPKET LREVLHLLRS TGNTQVEYMI
541: RIMKKWAKEN RVSI