1.I.1.1.4 Ciliate nucleopore complex, NPC. Regulates protein import and nuclear division (Malone et al. 2008). The NPC contributes to nucleus-selective transport in ciliates (Iwamoto et al. 2009). The transmembrane components, Pom121 and Pom82, localize exclusively to the macro (MAC)-
and micro (MIC)-nuclear NPCs, respectively. Functional nuclear dimorphism in ciliates is likely to depend on compositional and structural specificity of the NPCs (Iwamoto et al. 2017).
|
Accession Number: | D3KYT9 |
Protein Name: | Nucleoporin Nup50 |
Length: | 414 |
Molecular Weight: | 45667.00 |
Species: | Tetrahymena thermophila [5911] |
Number of TMSs: | 1 |
Substrate |
molecule, protein polypeptide chain, (ribonucleotide)n+m |
---|
1: MSKRRAPYEL DQNNLSDDEH AAPDLGRIST PEEIAQRRIL KIKGPKSEES TTPAKLVLLE
61: KLEDAQPAAN NNGNHANEAK EGTNGDKIEE KKIEFSTSSS LFAKTDATNG NNKHTENKEE
121: SKPEQSEKET EKVSEPAKEK TTNDTSLFGS IKPSSATSGL FGNTSTTGGL FGKSTGTGTL
181: FGNSNSLFTP SSGTGLFSNA NKVEGGQTIQ NIFNTDKPTG SLFGSLPTSN ATSLFGNAKP
241: AESSSLFGDL KNNTTGGLFS NIKSKGSDDE GDEGEGEDDD ELEHSPEIDP SQIQMKYQYD
301: NPYEKVIDKS VLKVRRGDGD ILEKGYISFE KFKADDKTPN ILVYRDQIKK VIFTIVVTKK
361: INKAEKIQNS TKNLKFIFYK KQDEKFVPDI IKVQFHDEKD GEEFYNKFQE YTQN