1.I.1.1.4
Ciliate nucleopore complex, NPC. Regulates protein import and nuclear division (Malone et al. 2008). The NPC contributes to nucleus-selective transport in ciliates (Iwamoto et al. 2009). The transmembrane components, Pom121 and Pom82, localize exclusively to the macro (MAC)-
and micro (MIC)-nuclear NPCs, respectively. Functional nuclear dimorphism in ciliates is likely to depend on compositional and structural specificity of the NPCs (Iwamoto et al. 2017).
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| Accession Number: | D3KYX7 |
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| Protein Name: | Nucleoporin gp210 |
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| Length: | 1927 |
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| Molecular Weight: | 218980.00 |
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| Species: | Tetrahymena thermophila [5911] |
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| Number of TMSs: | 1 |
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| Substrate |
molecule, protein polypeptide chain, (ribonucleotide)n+m |
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1: MNRIAFALLA ISCILIGGVT AIKTVDNQKK VNKLNLLLPE LYEDLEIRAP QFLLEASNGC
61: YTWSSSRPDF LQINGISDEV NPVCESTALV KLNNIRPYDN IIWISVTDKD TGDVMRVESK
121: IAKVQKIEIL TKLRTIDVGD LSVLEIIGYD KEGNSFSSLE GLRFEWSIQQ EENIFEFITF
181: KESKINTSPL RKKLEGYHFQ TDIIVIKALQ TGKADVTVKI KELGQTLVSL PVTLYAIDKF
241: DIYPGNDLYL LPQTILQYEL YFTKKATDNK IKLPSNDYNW KILDEKIGQI HQNGQLLTFE
301: EKRDVPTKVI VRPSKQVDYQ VTSTVTVVYP HSLEIFSREY TADSWESARR GYYQEIFEKS
361: THFVRNREYY LRVVLYDINK NEIKITPNVR IDVIIDKTKF DVIEQRNHEL RVRPKVLTNS
421: TVVAAQLIEV KGKTQNSETI WKPEKEIKNR VNISIVMPLK LFKPGNFIHL PLHSEQIFKL
481: KVVGGSGQYE WDTSNTTIAV TSYNRVHPKS IGSAKLHVSD KMNEKNFDEI EVIVSNVLRA
541: APLEQMKEVL INGYESTFAI AYPELGSQRF SNCSALAFSV EENSFYSSSA ERFQTYEEIL
601: KDLNKLMADN QFIKQELKKN ELKSFNEEFK EYIQSRSVTQ EEIDNVHYEY NNYGYCSAFR
661: ILAKEAGEYR ARIYAEGLQL QENVDQYISV KVLLPFKNII NPKYFSFFKK DEVIISMGSS
721: YNWRFKHGPS QWESWRKINV NTQVNLKQKG CAGQEGLISN IPKQTTQGNI TQSYQLTCGL
781: CKTDKENSYT ISISAQNEAD AKLPRPLVLH NELIVWCNVP HALYIYPLTS PNQRDSDDES
841: VLLQHAKTSK FNKYHLQTEM NHFFFTQVFD SRSLPFANYT SLAIGWKITT SECGPLTNLH
901: FSEYKDQFKL SLNTEQIPQK KDEFRKYELN TCVNFANQQN TDVIKIQATS ATLEDPQTSP
961: VSFSVNDEIL IAVSKNVECD PVESLLYNHK ENKYVMNLMY GSGQYIIHNN ATDVVQHKYH
1021: DSQSKLAFVT FKNGVSSLKI EDSLQIGAKR IECRVQVRDP ARIDLRLIQD IIPVGAYTQA
1081: VVEVYDDQGR KYTNSQVALM DIYLESDTSD NEGITLAIKR DPLNGHKFSI DGKKRGNYRL
1141: VAVLKSGSAS TYNDPRYANF FIIKSNSLDL EVFPPLEAYP PKIILHPNCQ TSLQLIGGPS
1201: DSTRVRYSSE TQNHQGSQKL IDLNQLDTKL YDIRALEKAK GNSTLEFFIH LQPNNTLLSK
1261: ITVPVTVQNI DDVKIFGMND RTLHQSTTVR LIAQMFIQGE LMTVGICPLS ISWQSKLEGV
1321: LRISQNISPE ILSAADIESS NKNQVSIGDS HLYAVNATAV DVGVAEIELT VTFIGQKSHV
1381: RTVARIDVIN PLSIPIPTYV AYSDIKPSIL LIPPKSGYFM PIQNPLKYTF VTACGSSDQY
1441: ETVRVDQNGH ITTGDKKGVS THIRAVSNSL QQEIMSVHVY TTSIYSLFVE NSHEVINMQV
1501: EGETTLQVRM QDFLGRSFPT RLDNVHLRVK VTNTKVLSAT ISDGSLLNLR AISSGHSICI
1561: VYLEANPHIY DIFFINVGSI VSPSSPVFVH TGGSVQFSVL QAKSSGDRYN SKRWSSSNEN
1621: VLTIDSNRGL AKAHQPGEVL VQYNDVVVYK SKVIVQEVGE IVRGDIGKNN RLTNEPSHPD
1681: YATRYVIPFQ IFLKDRSGSK ELLKRLENSI DKNPINNNLS WSCKAEHSEW FQVQGEVIDL
1741: PNGNQQAQCI VKLVEPNNYQ TMNMPPSLIL ITTISSRNQD AKFSFVQEHK FNDVIWKIHL
1801: SNNEKYIELN RAMNKQEIYI QTTFPLDISF GGNDIKPHVI SKFFEQKSVQ KIEIQISPEF
1861: NQNIDNKIYV KHPLTGQTEA IRVIYDPESS TPPTPGDSSP LTWTDYLITI ILICVTIIVV
1921: QNLSKNK