1.I.1.1.4
Ciliate nucleopore complex, NPC. Regulates protein import and nuclear division (Malone et al. 2008). The NPC contributes to nucleus-selective transport in ciliates (Iwamoto et al. 2009). The transmembrane components, Pom121 and Pom82, localize exclusively to the macro (MAC)-
and micro (MIC)-nuclear NPCs, respectively. Functional nuclear dimorphism in ciliates is likely to depend on compositional and structural specificity of the NPCs (Iwamoto et al. 2017).
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| Accession Number: | D3KYX9 |
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| Protein Name: | Nucleoporin Nup308 |
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| Length: | 2675 |
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| Molecular Weight: | 307942.00 |
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| Species: | Tetrahymena thermophila [5911] |
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| Substrate |
molecule, protein polypeptide chain, (ribonucleotide)n+m |
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1: MAANTGGGLF GGQQTQQNQG LFGGQQTQQN SSLFGGQQAQ NQQQGQGAQG QQQAFSLFTN
61: NQQGQNNQQA SSNQQNIFGG AIQQQQGGGN LFGQTQQSQQ QGTGQPSGLF GGIGNMNQQP
121: AAKQNETPVP PQTQNQLFAN IQNQQQPPQQ QTQNQGQQSQ QQQQQPTSTN GLFGNVQLGA
181: SNQNQAQNNT QNQQAEKPNS LFGDKQNQGA PQVTGGLFGN SANQGTGMQI NTNKPATSGL
241: FGANQTDQQQ NKPIGGGIFN QMQQNAQSQQ TQQQQQPPTQ TGGGLFGQTQ QQQQTNAPPK
301: EEPKTSLGGL NLLGQAPLNT QNQQNQAPKQ PAQSGGLFAQ APQQQQQQQQ QQQQNNTQPT
361: TTTTIPSTNS LFNNAPNTQA GATTTQTAQT TQTAAAPPKS QGPSLFAQNN QQTAQPPANS
421: QPTQQGQTQG GGLFGANIDA QNAGSSQPKF LNIGANKDNI LGQGKTNQPE GLNIGGGQKG
481: ILTGASGAAA TTTTTAASTT DATKPAQPSI LTGQTQAASS LLGGQQKPAT NPPTIGATSQ
541: TTGGLVGTGL AGQSNQIPAP KKTHQHTSQA TGPDERLEMD INSAKNLNGS LHMFCQNIHK
601: YKPEHVKKFF SNEDIFNKLT QGLQIYKGEQ NTDQWENIKK EAKEGKTPLK FWSERLSKYK
661: YQYLIVMFIE DIAEYLQIKP MDCYRMFDVF LSHESKFVDY FFNPSSNEPC IEFFYEQQAI
721: LFESNNVAVR KDSPFIINLK TSFMKDIYFH ERNCILASLR LLLLFTDDQY NYDAVRDVVA
781: RLLRNKLEES LWEQYAGQNN NPELSAEDSE LFQLQKQFEN DQIIKLLFII TQKNQSKISI
841: ETYLQKFNSQ NFMGNWQNLQ PQNENTFENK NKINELSTVV GDSCLMLVFA KVKEIQQNKN
901: KNEKDAFEKI FKQSQTSSQK SQQMNVLKLY YDSISQEQLV VEFYEQIEYL YKTIVRILNY
961: KNLGTLKTQW QEIFFELLVK IIQGINANEF YEEMDEQLES FISECICIAF SKTIHKNPKL
1021: IDLFWEKLES REQTKHFQNI FSSPISIYKV MKSALGMSSD PKSRHVIIFL TTLSNFNWIN
1081: FNQIADSQQN LDTASILKLR LIYKLIITDP KCINLLQYVF YFTDLSQNTF DQYINECNGD
1141: EVIKFVIKSF ALYNDLRSYA YQNFFAGLKA LNVLLNNHQY QTQQILQIEE YQDLLFKEYR
1201: RLAIQNDVTA TEYRLKCKRE ILNILYTILK DFEEPLLAFS QIKGMERNTE YDSPLLAHLF
1261: LFFTSFIEDW EQNQGALYLK HKWKIGSLIM KITDICLNRL SINVYKKQDF RPVQSDSYTS
1321: FFLHNFLCNQ LKKIRVDEMI IKVLEVAANQ SSISNNKINN KTLKLNNKYW QTYIMNTSNK
1381: FKEHQVEHIK NQVNLRNLIV DTLKVLETTM QLIEQKIQIR KQDFEYRFLQ KSMLLDEIPI
1441: LDFFERIICK SDCIFHYKQE YYIDSSLNSI KINILYAISS YINFENHFYS SNDEVNPTLP
1501: FYIYNFLESE GNLINQLADT HYLLDYDTIR NPLNNSRLPN GTYCELISSL SLRILTQIML
1561: AWEAQQSIRK PILVDFLSNM NMENYWEKLN YSSINTQLTN FIIEMFNILK LNEYDSNNDS
1621: EALRKNISDN SCAVIDFMLT ALYTQPLFMN LILKPDNLNR KKKDNDLKIR FKRFFESNVC
1681: TYDMRLLNKY LNLLVEIFKR DQMYPSFCQE FRQDTQYIFE KITKVVVQNF KPYEIDQLVE
1741: RDLYFLNSPK EPNIPYFEFQ KLKLSQLLRE HIKQTELYQQ MICLHSFQIL LDLISKEYLS
1801: NKCKSVQSIQ NSLKAIFENK QVNHIMNSLS KFAPSYSLDL WPVPQQIQTK MNIENEEQFK
1861: GKIFQQSFFY LLETNQYSYG RGYALDASEI IFNKIDAERP QDYLSRAKYI LFKLIEFRQK
1921: SIKWSIEEIK LRTFDSWIRL FCLVTSSGVE GYAMSTVQSS IPNFTLKQLR ERKIILEHEQ
1981: LCLLYPNYEI EFVSGFVNIF CASNPQCVGL FSNLQSEMMK QILQDLKKGY FGVLFDQKLK
2041: FLLYILFSLR HLQDLDYHSK ESENKKTQNP NNFIGRSNQN QESQHSFSDS YKKEEAEDLF
2101: KVMTQILEEA VHRGTRVQIC DFIQCLFLQL QVMEVLYLQT FQNNKKKFVI NENLNPYFTK
2161: IIGILMNLAA QNIDGLPILI SCLNSALHIY PQYFILQFKY QVKALEFLIN KIFYEKNETA
2221: QIFVSIINLL TDIAKYPEGA LLLSEANIVS MICNTPIFKN IENEPFYWQN GERNLLHSFW
2281: CWSLNFYKEY IISLPSDLEN TTSSFQFLQT YFTRIAKILS IPQVLQNTAT NLANNKMINT
2341: EQEKLSLAYM EEIELILELL SVYFCQANIF KRKMSNDFEQ ILQFLTHCTI CLFKQGLSIQ
2401: SIFMPVSKME KKLSQIYDIY QVSSADSAHL YHTSILTPSH TPNKQELEAG ISTAHSAIGD
2461: TKNKNYNLFI IQVELHYQSI LFSLFSCIQD GLQESSLLQL FQYSSNSFSD NLINNESKQV
2521: YSVNYWQSFA NSLFDCLKFV ENTLNKWDYK KNKNVNMDDQ LVKLRALTNS VEYNLCCYGF
2581: GSQTSLINSA KTIIQTSQFS LQAIVLSAIK HFQMLNEFKQ WFGHSIKDSL TDLQNKLNAK
2641: LDGLKKLEYE DIQLKKQIEE HILQFQRLSV TQDRY