1.I.1.1.4
Ciliate nucleopore complex, NPC. Regulates protein import and nuclear division (Malone et al. 2008). The NPC contributes to nucleus-selective transport in ciliates (Iwamoto et al. 2009). The transmembrane components, Pom121 and Pom82, localize exclusively to the macro (MAC)-
and micro (MIC)-nuclear NPCs, respectively. Functional nuclear dimorphism in ciliates is likely to depend on compositional and structural specificity of the NPCs (Iwamoto et al. 2017).
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| Accession Number: | D3KYY1 |
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| Protein Name: | Nucleoporin MicNup98B-Nup96 |
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| Length: | 2003 |
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| Molecular Weight: | 233014.00 |
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| Species: | Tetrahymena thermophila [5911] |
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| Substrate |
molecule, protein polypeptide chain, (ribonucleotide)n+m |
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1: MINNLFANNN TNQPNIFQNN NNQNNNNNSS NIFNRSGQNI FQSQNNNGQV NIFNANNNNN
61: QVGYQNQSQN IFQQNSNMNN ASSSNNNNIF GNNISNNNNY GGAQNNNIFN NNNQNMYQNS
121: NNPNALIGSQ RGKYELTKSP HTETQQNNQA GVIMNTSIIF CKGFEKMNPL LVRLEDYYLI
181: RTGKLSDAEK QKITSSIQIN SFNQNLITNL PQNFQPPNTQ ALNKDIRMVQ SQYVGNVNNN
241: NNIFNNNNNN GNNNNIFANN NNVNNSVNRN IFNNNNISTN NNINNNNNGN IFNNNNNNMN
301: NNGGNIFSGN NNQNNNVNNI FSFNNSQNNN MNKSNIFNNG NSTNNTSNIF QNNNTNMGNN
361: SIFQGNNNNN NNNIFRNDNS TNNTNLNIFS NNNNNINNSI FRNNNNNNTN IFNNGNNNGG
421: NNTSSIFNNS GSNNSVNIFR SNNNNNGGSI FSNNNNSSVQ NIFQKNNSSI FNNNNNNGGS
481: IFNNNNSIFG PNVQGGNIFQ NNNNNNFNNG NIFTNYNNPQ MYQSNLPGPA NGYYSIQSGM
541: YYAPTIQTGD LTRQQYLDLL EQEAEDKKVV KQSYFMPSFC PEEYAPAFRK KPIFKPFYVT
601: VQEEKGIRKL AKSLLPLQET IAKTQRGHSS ETTSNGKNDS FQLTQSAIKQ RKQMEEFNFY
661: KQPAQETKGR EMYARQQLSH TNPVSIKVEV LCSTLEGEEE EITLENQIDT LSKIKQIGLY
721: CKDHLLKMGK MKEDSRPYSF QIYYDGSLIR NQELLASDVF PVKLEATYQC EVIFLYDRYP
781: FMNTSDYIIN PPLEELQTYS LKELKNVHNF SVEGHYGKLE WQEPVDLTDL DIDKTIYIRD
841: QQIQVYPEVE YASKYKPKVG EGINNKCMIT YKNASSIQRK IKSGELNLQT VIKCIKKQSD
901: EQNVQFVKFD QKNLTWTILV DHFSGYQFNL DEQDDEENKE GQDSAANLQN VSSNSNPRSN
961: PSKQQQLIQG QQQFNQDSQR TANQQLQQQQ LQAENQFQQK INSSYQQLPM RQHIQNSNQF
1021: KQIYGQNEHQ PSETQKYINQ MREQQNVSKS QENSFIQQDY PITSHQQQNS NYQMNEHNQY
1081: QNQPSYMNRG QLQQQQYYGT HIDPSNDIII EEVENGSYNN TQADIDTLKS QAQELIEPVY
1141: QLPKTSYQQF LCQQNNEEQF VNLQNKQKPL NNFKDFKTRV DQRKNKIFQK EQQVPKCGVL
1201: YQSVKKHEIV ARGIQTLNQC LYQHSVKEYT FKGKKFYNDF SFCPSWNQNS YTSYSSQLKA
1261: IKKHTILPNN MGRIKIKDKQ RDQIEKYNNI VINGFLQSII DSQATNVIEN IDQITKLYTK
1321: DQGMSDTQIW STLPEIKIPT DNQYTLFLII YIKNYLLPVL SASKNNQNDL YQSLKEELSI
1381: LIMVNILFGN PQIDVISILK KVNKNSFSEN QWKVLFEGLR NNKMNQNEKV VQNLRKKQLK
1441: KYFEWKYSEN KVQINEQRAF LDRKEMKTQE EVEDAIIQCL KNHQIQNAIQ LADNYKLHTI
1501: SHLLTTFEQG SVENQIKQLN QDKYQNFNRI INFVSGNLEE LYKQSQRNEI SNLNKFACEI
1561: WYQKNQRQSL AETFDQFVQK VDKQIYDVDS RQQIISLEIL LLSLYAQHQL GENYVSKQLV
1621: NINIFAQINS LCYSQNRLDK RLSWFIIEFM NSIYFSNDKA LFKDKRARLM RGFLQQLQIL
1681: KKWKYELIVL IIMKDIIRKP QFISSIKNTF LRNCIPQISQ EDKSEVGQPN NLNNKFLIQS
1741: SNRDSSSDNS LEINKSFQID SENSNSVERL LYLIYTQYFH QSLGLYYYNS QIYQSALYHF
1801: MRDPNLTYLD ISNKILAYYE GPRIYLFGEQ NERQEIEKYL EQIAKKANLI FKYKYQSGLI
1861: KEVFSLLQSN NQDQYKQEYI NGIINLKDLL LETQNVLNLV IYPHQYQVIV DNQEFQSKNR
1921: RLQSKTDDSV TTLDNGGMLF QEFISFIFQQ LAEKVPDIRR YSQHYQTSGD IQQLLEIVSE
1981: HKAPKNEQIK HLILSTLKQN QYM