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3.A.18.1.1 The nuclear mRNA Export Complex (mRNA-E also called TREX) (including the exon junction complex) [TAP+p15 interact as a complex with the nuclear pore to facilitate mRNA transport to the cytoplasm] (Nojimma et al. 2007; Cheng et al., 2006)
Accession Number:	O00422
Protein Name:	Histone deacetylase complex subunit SAP18
Length:	153
Molecular Weight:	17561.00
Species:	Homo sapiens (Human) [9606]
Location¹ / Topology² / Orientation³:	Nucleus¹
Substrate	messenger RNA

Structure:
RefSeq:	NP_005861.2
Entrez Gene ID:	10284
Pfam:	PF06487
OMIM:	602949 gene
KEGG:	hsa:10284
Gene Ontology GO:0005737 C:cytoplasm GO:0000118 C:histone deacetylase complex GO:0003714 F:transcription corepressor activity GO:0006357 P:regulation of transcription from RNA polyme... GO:0006350 P:transcription
References (6) [1] “Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.” Zhang Y.et.al. 9150135 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The DNA sequence and analysis of human chromosome 13.” Dunham A.et.al. 15057823 [4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [5] “Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.” Tange T.O.et.al. 16314458 [6] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.” Gauci S.et.al. 19413330
2HDE

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT 
61:	WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM 
121:	TLQSQKFQIG DYLDIAITPP NRAPPPSGRM RPY

3.A.18.1.1
The nuclear mRNA Export Complex (mRNA-E also called TREX) (including the exon junction complex) [TAP+p15 interact as a complex with the nuclear pore to facilitate mRNA transport to the cytoplasm] (Nojimma et al. 2007; Cheng et al., 2006)

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

3.A.18.1.1The nuclear mRNA Export Complex (mRNA-E also called TREX) (including the exon junction complex) [TAP+p15 interact as a complex with the nuclear pore to facilitate mRNA transport to the cytoplasm] (Nojimma et al. 2007; Cheng et al., 2006)

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

3.A.18.1.1
The nuclear mRNA Export Complex (mRNA-E also called TREX) (including the exon junction complex) [TAP+p15 interact as a complex with the nuclear pore to facilitate mRNA transport to the cytoplasm] (Nojimma et al. 2007; Cheng et al., 2006)