8.A.137.1.2
Clathrin heavy chain 2 of 1625 aas, CLTCL1 CLH22, CLTCL, CLTD plus the sclathrin light chain B, CLCB. It impacts on Wnt/beta-catenin signaling by controlling exocytosis of transmembrane proteins including cadherins and Wnt co-receptors that together control the membrane-bound and soluble pools of beta-catenin (Munthe et al. 2020).
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| Accession Number: | P09497 |
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| Protein Name: | Clathrin light chain B |
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| Length: | 229 |
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| Molecular Weight: | 25190.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Cytoplasmic vesicle membrane1 / Peripheral membrane protein2 / Cytoplasmic side3 |
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| Substrate |
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1: MADDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DEGFGAPAGS HAAPAQPGPT
61: SGAGSEDMGT TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ RKRLQELDAA
121: SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRIADKA FYQQPDADII GYVASEEAFV
181: KESKEETPGT EWEKVAQLCD FNPKSSKQCK DVSRLRSVLM SLKQTPLSR