1.G.19.1.1
The rotavirus A membrane fusion protein complex including VP5 and 8, derived by proteolysis of VP4, as well as VP7, VP6 and VP2. VP5, 8 and 7 may play primary roles while VP6 and 2 play secondary roles (Gilbert and Greenberg 1998; Golantsova et al. 2004; Settembre et al. 2011; Elaid et al. 2014). These proteins from different viral strains may be very divergent in sequence.
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| Accession Number: | P12473 |
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| Protein Name: | Outer capsid protein VP4 |
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| Length: | 776 |
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| Molecular Weight: | 86554.00 |
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| Species: | Rotavirus A (strain Monkey/United States/RRV/1980 G3-P5B[3]-I2-R2-C3-M3-A9-Nx-T3-E3-H6) (RV-A) [10969] |
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| Location1 / Topology2 / Orientation3: |
Virion1 |
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| Substrate |
molecule |
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1: MASLIYRQLL TNSYTVDLSD EIQEIGSTKT QNVTINLGPF AQTGYAPVNW GPGETNDSTT
61: VEPVLDGPYQ PTSFNPPVDY WMLLAPTAAG VVVEGTNNTD RWLATILVEP NVTSETRSYT
121: LFGTQEQITI ANASQTQWKF IDVVKTTQNG SYSQYGPLQS TPKLYAVMKH NGKIYTYNGE
181: TPNVTTKYYS TTNYDSVNMT AFCDFYIIPR EEESTCTEYI NNGLPPIQNT RNIVPLALSA
241: RNIISHRAQA NEDIVVSKTS LWKEMQYNRD ITIRFKFASS IVKSGGLGYK WSEISFKPAN
301: YQYTYTRDGE DVTAHTTCSV NGMNDFNFNG GSLPTDFIIS RYEVIKENSY VYVDYWDDSQ
361: AFRNMVYVRS LAANLNSVIC TGGDYSFALP VGQWPVMTGG AVSLHSAGVT LSTQFTDFVS
421: FNSLRFRFRL TVEEPSFSIT RTRVGGLYGL PAAYPNNGKE YYEVAGRLSL ISLVPSNDDY
481: QTPITNSVTV RQDLERQLGE LREEFNALSQ EIAMSQLIYL ALLPLDMFSM FSGIKSTIDA
541: AKSMATSVMK KFKKSGLANS VSTLTDSLSD AASSISRGAS IRSVGSSASA WTDVSTQITD
601: VSSSVSSIST QTSTISRRLR LKEMATQTEG MNFDDISAAV LKTKIDRSTQ ISPNTLPDIV
661: TEASEKFIPN RAYRVINNDE VFEAGTDGRY FAYRVETFDE IPFDVQKFAD LVTDSPVISA
721: IIDFKTLKNL NDNYGISRQQ AFNLLRSDPR VLREFINQDN PIIRNRIEQL IMQCRL