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5.A.3.5.1
Thiosulfate reductase, PhsABC (Heinzinger et al., 1995) (Clark and Barrett 1987). Menaquinone is the sole electron donor. The endoergonic reduction reaction is driven by the pmf by a reverse loop mechanism (Stoffels et al. 2012). The enzyme can catalyze oxidation of sulfide to sulfite and sulfite to thiosulfate in an exergonic reaction that is pmf-independent (Stoffels et al. 2012). Because the endoergonic reaction is dependent on the pmf, there may be a proton channels in the complex, (possibly subunit C) that allows proton flux into the cell, coupled to the reduction reaction.

Accession Number:P37602
Protein Name:Thiosulfate reductase cytochrome B subunit
Length:254
Molecular Weight:28547.00
Species:Salmonella typhimurium [90371]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate electron

Cross database links:

RefSeq: NP_461008.1   
Entrez Gene ID: 1253584   
BioCyc: MetaCyc:MONOMER-12543    STYP99287:STM2063-MONOMER   
KEGG: stm:STM2063   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0022904 P:respiratory electron transport chain

References (3)

[1] “Sequence analysis of the phs operon in Salmonella typhimurium and the contribution of thiosulfate reduction to anaerobic energy metabolism.”  Heinzinger N.K.et.al.   7751291
[2] “Cloning and characterization of a gene cluster, phsBCDEF, necessary for the production of hydrogen sulfide from thiosulfate by Salmonella typhimurium.”  Alami N.et.al.   7737516
[3] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTIWGAELH YAPDYWPLWL IYAGVVVLLM LVGLVIHALL RRMLAPKTAG GEEHRDYLYS 
61:	LAIRRWHWGN ALLFVLLLLS GLFGHFSLGP VALMVQVHTW CGFALLAFWV GFVLINLTTG 
121:	NGRHYRVNFS GLVTRCIRQT RFYLFGIMKG EAHPFVATEQ NKFNPLQQLA YLAIMYALVP 
181:	LLIITGLLCL YPQVAGLGPV MLVLHMALAI IGLLFICAHL YLCTLGDTPG QIFRSMVDGY 
241:	HRHRTAPRGD KSAV