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3.A.1.143.1
The exoprotein (including α-amylase) secretion system, EcsAB(C) (Leskelä et al., 1999). Also may play roles in sporulation, competence (Leskelä et al., 1996) and transformation using purified DNA (Takeno et al., 2011). An involvement of EcsC in transport is not established, but it is similar in sequence to the C-terminus of the P-type ATPase, 3.A.3.31.2.

Accession Number:P55339
Protein Name:ABC-type transporter ATP-binding protein EcsA
Length:247
Molecular Weight:27722.00
Species:Bacillus subtilis (strain 168) [224308]
Substrate proteins

Cross database links:

eggNOG: COG1131
Entrez Gene ID: 936293   
Pfam: PF00005   
KEGG: bsu:BSU10040   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0030420 P:establishment of competence for transformation
GO:0030435 P:sporulation resulting in formation of a cellular spore
GO:0006810 P:transport

References (3)

[1] “Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC transporter with a role in exoprotein production, sporulation and competence.”  Leskela S.et.al.   8581172
[2] “The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.”  Noback M.A.et.al.   9579061
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSLLSVKDLT GGYTRNPVLK NVSFTLEPNQ IVGLIGLNGA GKSTTIRHII GLMDPHKGSI 
61:	ELNGKTFAED PEGYRSQFTY IPETPVLYEE LTLMEHLELT AMAYGLSKET MEKRLPPLLK 
121:	EFRMEKRLKW FPAHFSKGMK QKVMIMCAFL AEPALYIIDE PFLGLDPLAI NALLERMNEA 
181:	KKGGASVLMS THILATAERY CDSFIILHNG EVRARGTLSE LREQFGMKDA ALDDLYLELT 
241:	KEDAGHE