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|---|---|
| Accession Number: | P61326 |
| Protein Name: | Protein mago nashi homolog aka MAGOH |
| Length: | 146 |
| Molecular Weight: | 17164.00 |
| Species: | Homo sapiens (Human) [9606] |
| Location1 / Topology2 / Orientation3: | Nucleus1 |
| Substrate | messenger RNA |
Cross database links:
| RefSeq: | NP_002361.1 |
|---|---|
| Entrez Gene ID: | 4116 |
| Pfam: | PF02792 |
| OMIM: |
602603 gene |
| KEGG: | hsa:4116 |
Gene Ontology
GO:0005737
C:cytoplasm
GO:0035145
C:exon-exon junction complex
GO:0016607
C:nuclear speck
GO:0005681
C:spliceosomal complex
GO:0005515
F:protein binding
GO:0003723
F:RNA binding
GO:0006397
P:mRNA processing
GO:0051028
P:mRNA transport
GO:0000184
P:nuclear-transcribed mRNA catabolic process,...
GO:0006417
P:regulation of translation
GO:0008380
P:RNA splicing
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References (21)[1] “The mammalian homologue of mago nashi encodes a serum-inducible protein.” Zhao X.F.et.al. 9479507 [2] “Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.” Zhang Q.-H.et.al. 11042152 [3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [4] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “MAGOH interacts with a novel RNA-binding protein.” Zhao X.F.et.al. 10662555 [7] “Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.” Jurica M.S.et.al. 11991638 [8] “A novel mode of RBD-protein recognition in the Y14-Mago complex.” Fribourg S.et.al. 12730685 [9] “Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex.” Bono F.et.al. 14968132 [10] “Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.” Gehring N.H.et.al. 16209946 [11] “The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.” Ballut L.et.al. 16170325 [12] “Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.” Tange T.O.et.al. 16314458 [13] “PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.” Diem M.D.et.al. 18026120 [14] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.” Gauci S.et.al. 19413330 [15] “Disassembly of exon junction complexes by PYM.” Gehring N.H.et.al. 19410547 [16] “Assembly and mobility of exon-exon junction complexes in living cells.” Schmidt U.et.al. 19324961 [17] “Lysine acetylation targets protein complexes and co-regulates major cellular functions.” Choudhary C.et.al. 19608861 | |
| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MESDFYLRYY VGHKGKFGHE FLEFEFRPDG KLRYANNSNY KNDVMIRKEA YVHKSVMEEL 61: KRIIDDSEIT KEDDALWPPP DRVGRQELEI VIGDEHISFT TSKIGSLIDV NQSKDPEGLR 121: VFYYLVQDLK CLVFSLIGLH FKIKPI