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3.A.1.12.3
Choline porter

Accession Number:Q45461
Protein Name:OPBB aka OpuBB aka PROW
Length:217
Molecular Weight:23163.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate choline

Cross database links:

RefSeq: NP_391252.1   
Entrez Gene ID: 936225   
Pfam: PF00528   
KEGG: bsu:BSU33720   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006865 P:amino acid transport

References (3)

[1] “Characterization of a chimeric proU operon in a subtilin-producing mutant of Bacillus subtilis 168.”  Lin Y.et.al.   7592481
[2] “Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.”  Kappes R.M.et.al.   10216873
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MHHIVQFLQT NGGELLYKTY EHITISLIAV ILGVLVAVPL GVVLTRMKKG AGTIIGIVNI 
61:	IQTLPSLAIL AFFIPLLGVG KVPAIVALFF YSVLPILRNT YTGIRGVNKN LLESGKGIGM 
121:	TPAEQVRLVE LPLAAPVIMA GIRTSTIYLI GWATLASFIG GGGLGDYIFI GLNLYQPEYI 
181:	IGGAVPVTIL AIVIDYVLAV AERKLTPAGM QRLKELS