1.A.131.1.5
Inner membrane TRP Ca2+ channel, TrpR, of 1134 aas and ~9 TMSs. TrpR works as a Golgi membrane calcium ion channel that influences cell wall integration (Wang et al. 2021). It performs important roles in conidiation and in adapting to cell wall disruption reagents in a high temperature-induced defect-dependent manner, especially under calcium-limited culture conditions (Wang et al. 2021).
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| Accession Number: | Q5ARD4 |
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| Protein Name: | Integral membrane protein (AFU_orthologue AFUA_7G01610) |
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| Length: | 1134 |
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| Molecular Weight: | 125545.00 |
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| Species: | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) [227321] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MDFDYNARWH EEPWSSTVSH RPQSKQHLGR PSTRQHRKWR DTFRRRPRRR TSFGLGLWWM
61: ILVILSVMSS ASAALLEFEN CLDESIVDSS PRQLQFVPLD VWVTLNMTNS LYPLDVIVYG
121: NVTGTANRSA EYPAPDDPQW DNPNSTFGKI IDLDVDNNNY STLIASIQVA SFTPYSEPSR
181: FCDSVTQGDC PLGPVFYVNE TDLSTLRAFS VHHDMVSSYH FSTLHTTFTI ISGDAAADRL
241: GCISVSITPD LGSTVKNVLA FVPLSILVLV GLATISAAIY SPWGTTDPFR WTSNYGRDED
301: VLRLVTPGFG DCLQYIQFVV LTGALSLNYP GYYQPVISQA AWSSLMFNQS FFGTERNPVV
361: DGVYAVNGTR GLDRLERFVG MDGARDLWPG MMVWLCSIVG ITILLIQFAF AFRWLYRELA
421: RIPEEDLRAK NMPFTVGNVI RIVYNFFLLP LISLSFFQLI VASESPAYCV ALAGVVIFIL
481: ICFSIWIIRL IITTRPRSYL FDDLPTVLLY GPLYNTFSDD AAAYAVIPIF ISFARGVAIG
541: AVQASGIAQI VLLAICEVVS VLTIIAFRPF PSPSSMNLYH ICISIVRFLT ILLSIVFVPS
601: LGISQAARAW IGYVILLLHG LVLVFGFFLN ALQTLVEVTA RLLGAGGNEA GATRGGLVKL
661: TKFQVFGMRQ LSRRLPRRDV VTRQSMASDA AMLAHTDDRL SSQFEGSRPR SLSGSSALLL
721: NRATLNESKG SAIYDAGERS HSRTNSAGLY TPTTLGGFQG SGYQTTGSNS PKIGPIFAMQ
781: PHDPYYRPPR PRKRTGFSED SGRRRSSTLL RDADMDDDAI EGPSISRRGT PTPAYIPAPK
841: DDLDYDEPRR SRKDYAVREV DFYYRVRGPP LSHTGTRKLK TGPADPTGPV SSATGFFRNL
901: FSGKTKDKGK GFEVVRSTRA PPPGLIPERE EVHEPYTDEP GEQDTAHRDK SAPENDSVRH
961: ESDRRQDDEH ESPQLSLPLI DAGGTIELPS RMGSRRDTQC PPLAPKTPSV SSERRASQGA
1021: LDRNEDDQGD DSSLRPVQPS ARLPFSANSS PSRDRNYSLA STSASISSGH ERTAQSRIER
1081: PSSVGYVAQH RTRDNIHQGH AEEPSFTESA AELVNETPSE GNRSQPSRAS SRYT