| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.A.148.1.1 | Pore-forming protein after proteolysis to yield peptides. Four such peptides have been released and shown to form pores in the parasitophorous vacuole of T. gonadii (Jastrab and Darwin 2015; Bitew et al. 2024) (see family description). This protein is GRA47 (gene ID TGGT1_254000 = EPR59035.1) and has two TMSs near the N-terminus (residues 50 and 170) separated by a semi hydrophobic sequence that could resemble a P-loop as in members of the VIC (voltage-gated ion channel) (TC# 1.A.1) protein members. The same characteristic is observed for other members of this family. | Eukaryota |
Apicomplexa | PIL98022.1 pore-forming protein (peptide) of Toxoplasm gonadii |
|
1.A.148.1.2 | Uncharacterized protein of 544 aas with 2 TMSs and a possibly P-loop between them. | Eukaryota |
Apicomplexa | |
|
1.A.148.1.3 | Uncharacterized protein of 521 aas and 2 TMSs at residues 50 and 220 with a possible P-loop between them. | Eukaryota |
Apicomplexa | UP of Besnoitia besnoiti |
|
1.A.148.1.4 | Uncharacterized protein of 417 aas with possibly 2 TMSs | Eukaryota |
Apicomplexa | UP of Cystoisospora suis |