1.A.25.3.9
Zar1 resistosome of 852 aas and possibly about 3 TMSs of low hydrophobicity, is a calcium-permeable channel that triggers plant immune signalling (Bi et al. 2021). It forms a pentameric channel. It is a nucleotide-binding leucine-rich repeat receptor (NLR protein). Homologues in animals are called inflammasomes (Davis et al. 2011).
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| Accession Number: | Q38834 |
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| Protein Name: | Disease resistance RPP13-like protein 4 |
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| Length: | 852 |
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| Molecular Weight: | 97040.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 |
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| Substrate |
calcium(2+) |
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1: MVDAVVTVFL EKTLNILEEK GRTVSDYRKQ LEDLQSELKY MQSFLKDAER QKRTNETLRT
61: LVADLRELVY EAEDILVDCQ LADGDDGNEQ RSSNAWLSRL HPARVPLQYK KSKRLQEINE
121: RITKIKSQVE PYFEFITPSN VGRDNGTDRW SSPVYDHTQV VGLEGDKRKI KEWLFRSNDS
181: QLLIMAFVGM GGLGKTTIAQ EVFNDKEIEH RFERRIWVSV SQTFTEEQIM RSILRNLGDA
241: SVGDDIGTLL RKIQQYLLGK RYLIVMDDVW DKNLSWWDKI YQGLPRGQGG SVIVTTRSES
301: VAKRVQARDD KTHRPELLSP DNSWLLFCNV AFAANDGTCE RPELEDVGKE IVTKCKGLPL
361: TIKAVGGLLL CKDHVYHEWR RIAEHFQDEL RGNTSETDNV MSSLQLSYDE LPSHLKSCIL
421: TLSLYPEDCV IPKQQLVHGW IGEGFVMWRN GRSATESGED CFSGLTNRCL IEVVDKTYSG
481: TIITCKIHDM VRDLVIDIAK KDSFSNPEGL NCRHLGISGN FDEKQIKVNH KLRGVVSTTK
541: TGEVNKLNSD LAKKFTDCKY LRVLDISKSI FDAPLSEILD EIASLQHLAC LSLSNTHPLI
601: QFPRSMEDLH NLQILDASYC QNLKQLQPCI VLFKKLLVLD MTNCGSLECF PKGIGSLVKL
661: EVLLGFKPAR SNNGCKLSEV KNLTNLRKLG LSLTRGDQIE EEELDSLINL SKLMSISINC
721: YDSYGDDLIT KIDALTPPHQ LHELSLQFYP GKSSPSWLSP HKLPMLRYMS ICSGNLVKMQ
781: EPFWGNENTH WRIEGLMLSS LSDLDMDWEV LQQSMPYLRT VTANWCPELE SFAIEDVGFR
841: GGVWMKTPLH RT