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1.A.8.9.19
AQP2 (AQP9) of 312 aas and 6 TMSs; transports water, glycerol and urea as well as the drugs, melarsoprol and pentamidine (Schmidt et al. 2018). CCCP and gramicidin but not nigericin inhibit Trypanosoma brucei Aquaglyceroporins Aqp2 and Aqp3 at neutral pH (Petersen and Beitz 2020).

Accession Number:Q388I5
Protein Name:Aquaporin 9, putative
Length:312
Molecular Weight:33594.00
Species:Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [185431]
Number of TMSs:6
Substrate

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  • CDD Search (Conserved Domain Database)
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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQSQPDNVAY PMELQAVNKD GTVEVRVQGN VDNSSNERWD ADVQKHEVAE AQEKPVGGIN 
61:	FWAPRELRLN YRDYVAEFLG NFVLIYIAKG AVITSLLVPD FGLLGLTIGI GVAVTMALYV 
121:	SLGISGGHLN SAVTVGNAVF GDFPWRKVPG YIAAQMLGTF LGAACAYGVF ADLLKAHGGG 
181:	ELIAFGEKGI AWVFAMYPAE GNGIFYPIFA ELISTAVLLL CVCGIFDPNN SPAKGYETVA 
241:	IGALVFVMVN NFGLASPLAM NPSLDFGPRV FGAILLGGEV FSHANYYFWV PLVVPFFGAI 
301:	LGLFLYKYFL PH