| TCID | Name | Domain | Kingdom/Phylum | Protein(s) | ||
|---|---|---|---|---|---|---|
|
1.C.52.1.1 | Dermaseptin B1 precursor | Eukaryota |
Metazoa | Dermaseptin B1 of Phyllomedusa bicolor | ||
|
1.C.52.1.2 | Brevinin 2EF precursor | Eukaryota |
Metazoa | Brevinin-2EF of Rana esculenta | ||
|
1.C.52.1.3 | Gaegurin-4 precursor | Eukaryota |
Metazoa | Gaegurin-4 of Rana rugosa | ||
|
1.C.52.1.4 | Esculentin-1b precursor | Eukaryota |
Metazoa | Esculentin-1b of Rana esculenta | ||
|
1.C.52.1.5 | Temporin G precursor | Eukaryota |
Metazoa | Temporin G precursor of Rana temporaria | ||
|
1.C.52.1.6 | Temporin B precursor | Eukaryota |
Metazoa | Temporin B precursor of Rana temporaria | ||
|
1.C.52.1.7 | Ranatuerin-2P precursor | Eukaryota |
Metazoa | Ranatuerin-2P precursor of Rana pipiens | ||
|
1.C.52.1.8 | Tryptophyllin-1 precursor | Eukaryota |
Metazoa | Tryptophyllin-1 precursor of Pachymedusa dacnicolor | ||
|
1.C.52.1.9 | Caerin 1.1.5 precursor; similar to maculatin 1.1 of Litoria genimaculata (1.C.76.1.1) (Fernandez et al., 2008; Mechler et al., 2007). | Eukaryota |
Metazoa | Caerin 1.1.5 precursor of Litoria caerulea | ||
|
1.C.52.1.10 | PBN1 precursor | Eukaryota |
Metazoa | PBN1 precursor of Phyllomedusa bicolor | ||
|
1.C.52.1.11 | Preprofallaxidin-6 (green tree frog) (71% identical to 1.C.52.1.9). The NMR structure of the mature peptide (Fallaxidin 4.1a) reveals a helical structure in detergent solultions. Pore formation is established (Sherman et al. 2009). | Eukaryota |
Metazoa | Fallaxidin of Litoria fallax (B5LUQ8) | ||
|
1.C.52.1.12 | Phylloseptin-7 (orange legged leaf frog) (81% identical to 1.C.52.1.10). | Eukaryota |
Metazoa | Phylloseptin of Phyllomedusa hypochondrialis (P84572) | ||
|
1.C.52.1.13 | Raniseptin-1 (55% identical to 1.C.52.1.1). | Eukaryota |
Metazoa | Raniseptin-1 of Hypsiboas raniceps (P86037) | ||
|
1.C.52.1.14 | Kininogen-1 (71% identical to 1.C.52.1.10). | Eukaryota |
Metazoa | Kininogen-1 of Phyllomedusa sauvagei (Q800F1). | ||
|
1.C.52.1.15 | Vespakinin-M precursor (also homologous to Melittin) | Eukaryota |
Metazoa | Vespakinin of Vespa magnifica (Q0PQX8) | ||
|
1.C.52.1.16 | Brevienin-1E of 71 aas | Eukaryota |
Metazoa | Brevenin-iE of Pelophylex esulentus | ||
|
1.C.52.1.17 | Ranakinin-N of 58 aas | Eukaryota |
Metazoa | Ranakinin-N of Hylarana nigrovittata | ||
|
1.C.52.1.18 | Prepromelittin amphibian defense peptide | Eukaryota |
Metazoa | Prepromelittin of Rana andersonii (E3SZK1) | ||
|
1.C.52.1.19 | Rufosusi-spotted torrent frog Amolopin-3a anti-microbial peptide | Eukaryota |
Metazoa | Amolopin-3a of Amolops loloensis (A6XFB5) | ||
|
1.C.52.1.20 | Demaseptin-1 | Eukaryota |
Metazoa | Dermaseptin-1 of Phyllomedusa hypochondrialis (P84596) | ||
|
1.C.52.1.21 | Brevinin-2HS of 70 aas and 2 TMSs. | Eukaryota |
Metazoa | Brevinin-2HS of Odorrana schmackeri (Schmacker's frog) (Rana schmackeri) | ||
|
1.C.52.1.22 | Rhacophorin-2 of 72 aas and 2 TMSs. | Eukaryota |
Metazoa | Rhacophori-2 of Rhacophorus feae (Thao whipping frog) | ||
|
1.C.52.1.23 | Hainanensin-1 of 67 aas and 2 TMSs | Eukaryota |
Metazoa | Hainanensin-1 of Odorrana hainanensis (Odor frog) (Rana hainanensis) | ||
|
1.C.52.1.24 | Amurin-1 of 70 aas and 2 TMSs | Eukaryota |
Metazoa | Amurin-1 of Rana amurensis (Korean brown frog) | ||
|
1.C.52.1.25 | Viridimin-1 of 66 aas and 2 TM | Eukaryota |
Metazoa | Viridimin-1 of Amolops viridimaculatus (Dahaoping sucker frog) | ||
|
1.C.52.1.26 | Amolopin-1a of 70 aas | Eukaryota |
Metazoa | Amolopin-1a of Amolops loloensis (rufous-spotted torrent frog) | ||
|
1.C.52.1.27 | Andersonin of 72 aas | Eukaryota |
Metazoa | Andersonin of Odorrana andersonii (golden crossband frog) | ||
|
1.C.52.1.28 | Lividin-1 of 68 aas | Eukaryota |
Metazoa | Lividin-1 of Odorrana livida (green cascade frog) | ||
|
1.C.52.1.29 | Kunyuenin of 62 aas | Eukaryota |
Metazoa | Kunyuenin of Rana kunyuensis | ||
|
1.C.52.1.30 | Japonicin-1Ja of 61 aas | Eukaryota |
Metazoa | Japonicin-1Ja of Rana japonica (Japanese reddish frog) | ||
|
1.C.52.1.31 | Limnonectin-1Fa of 62 aas | Eukaryota |
Metazoa | Limnonectin-1Fa of Limnonectes fujianensis (Fujian large-headed frog) | ||
|
1.C.52.1.32 | Jingdongin-1 of 63 aas | Eukaryota |
Metazoa | Jingdongin-1 of Amolop jingdongensis (Chinese torrent frog)
| ||
|
1.C.52.1.33 | Frenatin-3 of 68 aas | Eukaryota |
Metazoa | Frenatin-2 of Litoria infrafrenata (Giant tree frog) (White-lipped tree frog) | ||
|
1.C.52.1.34 | Antimicrobial peptide odorranain B4 of 63 aas. A 15 aa disulfide bonded peptide, ORB-1 (LKGCWTKSIPPKPCF), too short to pass through a membrane, forms anion selective channels (Hu et al. 2015). | Eukaryota |
Metazoa | odorranain B4 of Odorrana grahami (Yunnanfu frog) (Rana grahami) | ||
|
1.C.52.1.35 | Pore-forming Ocellatin-PT1 of 66 aas (Gusmão et al. 2017). | Eukaryota |
Metazoa | Ocellatin-PT1 of Leptodactylus pustulatus (Ceara white-lipped frog) | ||
|
1.C.52.1.36 | Dybowskin-1ST antimicrobial peptide of 59 aas. It has an N-terminal TMS with a largely hydrophilic central region with an α-helical structure. It promotes wound healing and effectively inhibits the growth of Escherichia coli and Staphylococcus aureus (Liu et al. 2021).
| Eukaryota |
Opisthokonta | antimicrobial peptide of Rana dybowskii (Dybovsky's frog) (Korean brown frog) | ||
|
1.C.52.1.37 | Dermaseptin S1, Drs1, of 79 aas and 1 or 2 TMSs with the first N-terminal TMS being more hydrophobic than the second C-terminal TMS. The central region is very hydrophilic. It is 90% identical to Dermaseptin B1 (TC# 1.C.52.1.1) at the sequence level. It shows antimicrobial activity with potent activity against Gram-positive and Gram-negative bacteria, fungi and protozoa (Mor et al. 1991, Mor and Nicolas 1994). It also stimulates the microbicidal activity of polymorphonuclear leukocytes (Ammar et al. 1998) and may act by disturbing membrane functions with its amphipathic structure (Mor and Nicolas 1994). | Eukaryota |
Opisthokonta | Dermaseptin S1 of Phyllomedusa sauvagei (Sauvage's leaf frog)
| ||
|
1.C.52.2.1 | Ceratotoxin A, CtxA, of 72 aas and 2 TMSs. It forms one of the largest pores among the group of ceratotoxins (Mayer et al. 2019). | Eukaryota |
Metazoa | CtxA of Ceratitis capitata (medfly) (P36190) | ||
|
1.C.52.2.2 | Ceratotoxin-B of 29 aas, corresponding to the C-terminal region of Ceratotoxin A. | Eukaryota |
Opisthokonta | Ceratotoxin-B of Ceratitis capitata (Mediterranean fruit fly) | ||
|
1.C.52.2.3 | Ceratotoxin 2 of 40 aas and 1 N-terminal TMS. | Eukaryota |
Opisthokonta | Ceretotoxin 2 of Ceratitis rosa (Natal fruit fly) |