TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.124.1.1









The lysine exporter, LysO of 299 aas and 9 putative TMSs (Pathania and Sardesai 2015).  Also exports the toxic lysine antimetabolite, thialysine. Topological analyses of LysO revealed a critical role for a conserved pair of intramembrane solvent-exposed acidic residues (Dubey et al. 2021).

Bacteria
Pseudomonadota
LysO of E. coli
2.A.124.1.2









Uncharacterized protein of 306 aas and 9 TMSs.

Bacteria
Bacteroidota
UP of Bacteroides coprophilus
2.A.124.1.3









Uncharacterized protein of 307 aas and 9 TMSs.

Bacteria
Bacillota
UP of Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus))
2.A.124.1.4









Uncharacterized protein of 206 aas and 7 TMSs. Belongs to the CDD Asp-Al_Ex (asp/ala exchanger) family (TC#2.A.81)

Bacteria
Bacteroidota
UP of Bacteroides fragilis
2.A.124.1.5









Uncharacterized protein of 297 aas and 8 TMSs.

Archaea
Thermoproteota
UP of Pyrobaculum aerophilum
2.A.124.1.6









Uncharacterized protein of 198 aas and 6 TMSs.

Archaea
Thermoproteota
UP of Fervidicoccus fontis
2.A.124.1.7









Uncharacterized protein of 299 aas and 9 TMSs

Archaea
Thermoproteota
UP of Sulfolobus islandicus
2.A.124.1.8









Lysine-specific transporter, LysT of 302 aas and 8 TMSs (Jorth and Whiteley 2010).

Bacteria
Pseudomonadota
LysT of Aggregatibacter actinomycetemcomitans