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2.A.2.3.16
MfsD2B protein of 504 aas and 12 TMSs. It is a cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate from red blood cells and platelets (Vu et al. 2017). Sphingosine-1-phosphate is a signaling sphingolipid, and its export from red blood cells into in the plasma is required for red blood cell morphology. It does not transport lysophosphatidylcholine (LPC).

Accession Number:A6NFX1
Protein Name:Major facilitator superfamily domain-containing protein 2B
Length:504
Molecular Weight:53743.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MAAPPAPAAK GSPQPEPHAP EPGPGSAKRG REDSRAGRLS FCTKVCYGIG GVPNQIASSA 
61:	TAFYLQLFLL DIAQIPAAQV SLVLFGGKVS GAAADPVAGF FINRSQRTGS GRLMPWVLGC 
121:	TPFIALAYFF LWFLPPFTSL RGLWYTTFYC LFQALATFFQ VPYTALTMLL TPCPRERDSA 
181:	TAYRMTVEMA GTLMGATVHG LIVSGAHRPH RCEATATPGP VTVSPNAAHL YCIAAAVVVV 
241:	TYPVCISLLC LGVKERPDPS APASGPGLSF LAGLSLTTRH PPYLKLVISF LFISAAVQVE 
301:	QSYLVLFCTH ASQLHDHVQG LVLTVLVSAV LSTPLWEWVL QRFGKKTSAF GIFAMVPFAI 
361:	LLAAVPTAPV AYVVAFVSGV SIAVSLLLPW SMLPDVVDDF QLQHRHGPGL ETIFYSSYVF 
421:	FTKLSGACAL GISTLSLEFS GYKAGVCKQA EEVVVTLKVL IGAVPTCMIL AGLCILMVGS 
481:	TPKTPSRDAS SRLSLRRRTS YSLA