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2.A.2.4.1
Sucrose:H+ symporter, Suc1 or Sut1. It provides osmotic driving force for anther dehiscence, pollen germination and pollen tube growth and also transports other glucosides such as maltose and phenylglucosides. Km (sucrose)= 0.5 mM. (Stadler et al., 1999)).  In wheat (Triticum aesticum), there are at least three isoforms designated Sut2A, Sut2B and Sut2D (Deol et al. 2013). The ortholog in the common bean, Phaseolus vulgaris (SUT1.1), has been characterized as a high affinity sucrose:H+ symporter (Santiago et al. 2020). SUTs in rice play a role in the apoplastic loading as a major phloem loading strategy (Wang et al. 2021).  

Accession Number:Q39232
Protein Name:SucL aka SUC1 aka F17M19.3
Length:513
Molecular Weight:54858.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Sucrose

Cross database links:

Genevestigator: Q39232
HEGENOM: HBG587870
RefSeq: NP_177333.1   
Entrez Gene ID: 843519   
Pfam: PF00083   
KEGG: ath:AT1G71880   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005773 C:vacuole
GO:0008506 F:sucrose:hydrogen symporter activity
GO:0009846 P:pollen germination
GO:0009624 P:response to nematode
GO:0015770 P:sucrose transport

References (9)

[1] “SUC1 and SUC2: two sucrose transporters from Arabidopsis thaliana; expression and characterization in baker's yeast and identification of the histidine-tagged protein.”  Sauer N.et.al.   7920705
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “A kinetic model with ordered cytoplasmic dissociation for SUC1, an Arabidopsis H(+)/sucrose cotransporter expressed in Xenopus oocytes.”  Zhou J.-J.et.al.   9307438
[5] “His-65 in the proton-sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases transport activity.”  Lu J.M.-Y.et.al.   9671798
[6] “The AtSUC1 sucrose carrier may represent the osmotic driving force for anther dehiscence and pollen tube growth in Arabidopsis.”  Stadler R.et.al.   10476074
[7] “Sugar-induced increase in cytosolic Ca(2+) in Arabidopsis thaliana whole plants.”  Furuichi T.et.al.   11673631
[8] “Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.”  Shimaoka T.et.al.   15215502
[9] “Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis.”  Niittylae T.et.al.   17586839

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGAYETEKPT KDAAALETQS PEDFDQPSPL RKIISVASIA AGVQFGWALQ LSLLTPYVQL 
61:	LGIPHKWSSL IWLCGPVSGM IVQPIVGFHS DRCRSKFGRR RPFIATGAAL VAVAVFLIGY 
121:	AADFGYKMGD KLEEKVKVRA IGIFALGFWI LDVANNTLQG PCRAFLADLA AGDAKRTRVA 
181:	NAFFSFFMAV GNVLGYAAGS YTNLHKMFPF TMTKACDIYC ANLKTCFFLS ITLLLIVTVT 
241:	SLWYVNDKQW SPPPRNADDD EKTSSVPLFG EIFGAFKVMK RPMWMLLIVT ALNWIAWFPF 
301:	LLFDTDWMGR EVFGGDSDGN ERSKKLYSLG VQSGAMGLMF NSIVLGFMSL GVEWIGRKLG 
361:	GAKRLWGIVN FILAAGLAMT VLVTKFAEDH RKTAGDLAGP SASVKAGALS LFAVLGIPLA 
421:	ITFSTPFALA SIFSSCSGAG QGLSLGVLNL AIVIPQMIVS LGGGPFDALF GGGNLPAFIV 
481:	AAIAAAISGV LALTVLPSPP PDAPKATTMG GFH