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2.A.3.4.6 The thiamine (vitamin B₁) transporter, Thi9 (SPAC9.10). Uptake is inhibited by pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine indicating that these compounds are substrates of Thi9 (Vogl et al., 2008).
Accession Number:	Q9UT18
Protein Name:	SPAC9.10
Length:	591
Molecular Weight:	65070.00
Species:	Schizosaccharomyces pombe (Fission yeast) [4896]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	thiamine(1+)

RefSeq:	NP_593353.1
Entrez Gene ID:	2543578
Pfam:	PF00324
KEGG:	spo:SPAC9.10
Gene Ontology GO:0005783 C:endoplasmic reticulum GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015171 F:amino acid transmembrane transporter activity GO:0015234 F:thiamin transmembrane transporter activity GO:0006865 P:amino acid transport GO:0015888 P:thiamin transport
References (2) [1] “The genome sequence of Schizosaccharomyces pombe.” Wood V.et.al. 11859360 [2] “Phosphoproteome analysis of fission yeast.” Wilson-Grady J.T.et.al. 18257517

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MPSSQISHQD PELGQTSSGS SSIKEKAEPQ LYAGPIDPAR RPDVFQEGFE DVSVTDDDND 
61:	NELLRKMGYQ PVLHRSFEFF ESFAASFASL DVVSGVRLTF SWGISFGGPA AYWSAMLVTG 
121:	FCSIVTAACL AEICSALPAA GSIYLWAAES AGPRFGRFVS FLVAWWSTTA WTTFVASITQ 
181:	STANFIFAEV STFNNPWPTN DSDVKFRAVQ WIVAEVLLVF TILLNQVPPR YYKWIFKASM 
241:	LLMFIDYVMN IIWVPVATSK KPDGFRSAKW VFTETIYDQA GYIKEVDDAN GNPIASLSKI 
301:	VPKGWQWCLS YFATAGVIVG YDASGHIAEE TKDASIKAAR GIFYSTVTSF IVAFSLAILY 
361:	LFCCPDLDTF TAILYNDNSP QPFVNFYSYL LGRGGHVVMN VVIILEIFLN GVVSVLACSR 
421:	LVFAVSRDGV LPFSNWISQV SKTGQPKNAI TVIYIVSALL LCTILPSAVA FTSLVSAAGA 
481:	PSFAAYAVLA FCRLFITRDK FPKGRWSLGW LSKPCLVITL VYNLFALVVN VSPYTYPVTG 
541:	PSFNYAVVIM GGVSIFAIIC TIVIPKSRWV ANRYRYESDS EHSASVKELK V

2.A.3.4.6
The thiamine (vitamin B₁) transporter, Thi9 (SPAC9.10). Uptake is inhibited by pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine indicating that these compounds are substrates of Thi9 (Vogl et al., 2008).

Cross database links:

Gene Ontology

References (2)

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2.A.3.4.6The thiamine (vitamin B1) transporter, Thi9 (SPAC9.10). Uptake is inhibited by pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine indicating that these compounds are substrates of Thi9 (Vogl et al., 2008).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.3.4.6
The thiamine (vitamin B₁) transporter, Thi9 (SPAC9.10). Uptake is inhibited by pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine indicating that these compounds are substrates of Thi9 (Vogl et al., 2008).