3.A.1.121.7
Putative ABC protein of 684 aas and 0 TMSs, ATCF1. Found to be essential for bloodstream-form Trypanosoma brucei through a genome-wide RNAi screen (Schmidt et al. 2018).
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| Accession Number: | Q389P2 |
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| Protein Name: | ATP-binding cassette protein, putative |
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| Length: | 684 |
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| Molecular Weight: | 77698.00 |
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| Species: | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [185431] |
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| Number of TMSs: | 2 |
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| Substrate |
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1: MSSLSTAGCV GDANVLGDSD VKVSVLSRKD RKKQERTEKL LEEQRQLREQ ANCVNKDGDN
61: PFSVTWEHDK GTEGSRDISL QRVAVSVNGK VLFKDTQVRL SAGARYGLMG PNGRGKSTIL
121: RLLSSRELPV QSNLELLLVE QEQEFHESEV SAVQAVLQSH KKQREFASEA AQLHEKTELS
181: HEEMERLNFL EEELDIMGAA QAEARARRIL FGLGFPTEWH ERPTSSFSGG WRKRIALAAA
241: VFIEPDVLML DEPTNHLDLN AVIWLESYLC EQYNEKARRP KTLVVVSHDA GFLDEVCTHM
301: VHVENYQLNY YRGGFSGFDE QLRQRHQEID KKYATFNKTI NEKKRNGMSN AQVDEWIKDQ
361: VRTGRLDPIY LEKRRDYIVN FPFSEPPELP DGYIVKLEDV SFNYPGGPVL FHKVSCALWA
421: DSRITLCGPN GIGKSTLLSL LTGQLEPTEG IITMNRKVRI GRYNQHFVDK LPLEKTSVEF
481: IQSLGIREED KARRQLGSFG LEGIVHKNQI ATLSGGQKAR VALAAISAEK PHFLLFDEPT
541: NHLDVESIEA LCHAIKNFKG GVLVVTHDAR LIEETDMQIW EAGNQNVRPF NGSLNDYKNK
601: VRREFEEQEK KMLKERHIAT EEKQLNSRLA REGAGKDVAA LKKEKEEETR QRQLAELDAA
661: FALLDKRKKV KKVKKDKEEK ANDG