3.A.3.1.11
Na+,K+-ATPase α2 subunit, ATP1a2a or ATPA2A. Deficiency causes brain ventricle dilation and embryonic motility in zebra fish. Is essential for skeletal and heart muscle function (Doganli et al. 2012).
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| Accession Number: | Q90X34 |
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| Protein Name: | Na+/K+ ATPase alpha2 subunit |
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| Length: | 1017 |
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| Molecular Weight: | 112235.00 |
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| Species: | Danio rerio (Zebrafish) [7955] |
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| Number of TMSs: | 8 |
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| Substrate |
sodium(1+), potassium(1+) |
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1: MGKGYGHESS PEAAPTGGKR KKKDKDLDEL KKEVSLDDHK LTLDELSTRY GVDLARGLTH
61: KRAMEILARD GPNALTPPPT TPEWVKFCKQ LFGGFSILLW IGAILCFLAY SIQAATEDEP
121: VNDNLYLGVV LSAVVIITGC FSYYQEAKSS RIMDSFKNMV PQQALVIRDG EKLQINAEEV
181: VQGDLVEIKG GDRVPADLRI ISSSGCKVDN SSLTGESEPQ TRSPEFTHEN PLETRNISFF
241: STNCVEGTAH GIVIATGDHT VMGRIATLAS GLEVGQTPIN MEIEHFIHII TGVAIFLGMS
301: FFILSIILGY TWLEAVIFLI GIIVANVPEG LLATVTVCLT LTAKRMARKN CLVKNLEAVE
361: TLGSTSTICS DKTGTLTQNR MTVAHMWFDN QIHEADTTED QSGCDFDKSS PTWFSLSRVG
421: GLCNRAVFKA GQEEIPIRTR DTAGDASESA LLKCVEILSG NVETLRENNR KVAEIPFNST
481: NKYQLSIHEL EDSPTGHLLV MKGAPERILD RCSTIMINGE EFPIDDDWMD AFQGAYMELG
541: GLGERVLGFC HLFLSPSQFP RGFEFDCDDV NFPVNQLCFL GLISMIDPPR AAVPDAVGKC
601: RSAGIKVIMV TGDHPITAKA IAKGVGIISE GNETVEDIAE RLNIPLSQVN PREAKACVVH
661: GSDLKDMSSE YLDDILRNHT EIVFARTSPQ QKLIIVEGCQ RQGAIVAVTG DGVNDSPALK
721: KADIGVAMGI TGSDVSKQAA DMILLDDNFA SIVTGVEEGR LIFDNLKKSI AYTLTSNIPE
781: ITPFLLFIIA SVPLPLGTVT ILCIDLGTDM VPAISLAYES AESDIMKRQP RNPKTDKLVN
841: ERLISMAYGQ IGMIQALGGF FTYFVIMAEN GFLPQTLLGI RLDWDDRTVN DLEDGYGQQW
901: TYEQRKIIEF TCHTSFFVSI VVVQWADLII CKTRRNSVFQ QGMKNRILIF GLFAETALAA
961: FLSYCPGMDV ALRMYPLKIM WWFCAFPYSL LIFVYDEIRK FILRRNPGGW VEIETYY