TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.205.1.1









Transmembrane protein 65, TMEM65, of 240 aas with possibly 5 - 7 TMSs. There is one peak of low hydrophobicity peaking at residue 30, three more of substantial hydrophobicity between residues 120 - 190) and one C-terminal TMS at residie 220.  See family description for the functions and characteristics of this protein, probably relevant to other members of this family (Zhang et al. 2025).

Eukaryota
Metazoa, Chordata
TMEM65 of Homo sapiens
8.A.205.1.2









Uncharacterized protein of 392 aas and possibly 4 TMSs in a 1 (near the N-terminus) + 3 (towards the C-terminus). However, there are additional peaks of low hydrophobicity between these more hydrophobic regions.  

Eukaryota
Euglenozoa
UP of Trypanosoma vivax
8.A.205.1.3









Uncharacterized protein of 776 aas and 3 or 4 TMSs near the C-terminus of the protein, as well as 4 or 5 potential TMSs of low hydrophobicity near the N-terminus (residues 1 - 220).

Eukaryota
Metazoa, Mollusca
UP of Bulinus truncatus
8.A.205.1.4









Uncharacterized protein of 304 aas with 3 TMSs near its C-terminus (residues 130 - 250).

Eukaryota
Metazoa, Nematoda
UP of Caenorhabditis bovis
8.A.205.1.5









Uncharacterized protein of 501 aas and 1 TMS near the N-terminus (residues 50 - 70) as well as ~4 TMSs of low hydrophobicity between residues 300 and 400.

Eukaryota
Perkinsozoa
UP of Perkinsus olseni
8.A.205.1.6









Tmem65 protein of 729 aas with probably about 9 or 10 TMSs, 4 or 5 TMSs (residues 30 - 210) and 4 or 5 TMSs (residues 550 - end). 

Eukaryota
Tmem65 of Symbiodinium microadriaticum
8.A.205.1.8









GAF domain-related protein of 1179 aas with 4 or 5 N-terminal TMSs in a 3 + 1 or 2 TMS arrangement, all between residues 180 and 300. 

None
Apicomplexa
GAF domain containing protein of Plasmodium berghei