8.A.205.1.1 Transmembrane protein 65, TMEM65, of 240 aas with possibly 5 - 7 TMSs. There is one peak of low hydrophobicity peaking at residue 30, three more of substantial hydrophobicity between residues 120 - 190) and one C-terminal TMS at residie 220. See family description for the functions and characteristics of this protein, probably relevant to other members of this family (Zhang et al. 2025).
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Accession Number: | Q6PI78 |
Protein Name: | Transmembrane protein 65 |
Length: | 240 |
Molecular Weight: | 25498.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 3 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MSRLLPLLRS RTARSLRPGP AAAAAPRPPS WCCCGRGLLA LAPPGGLPGG PRRLGTHPKK
61: EPMEALNTAQ GARDFIYSLH STERSCLLKE LHRFESIAIA QEKLEAPPPT PGQLRYVFIH
121: NAIPFIGFGF LDNAIMIVAG THIEMSIGII LGISTMAAAA LGNLVSDLAG LGLAGYVEAL
181: ASRLGLSIPD LTPKQVDMWQ TRLSTHLGKA VGVTIGCILG MFPLIFFGGG EEDEKLETKS