8.A.245.1.1
VEGFA of 395 aas with two possible TMSs at residies 50 and 190. It induces permeabilization of blood vessels while preventing the
downregulation of KCC2 induced by axotomy in extraocular motoneurons (Capilla-López et al. 2024).
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| Accession Number: | P15692 |
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| Protein Name: | Vascular endothelial growth factor A, long form |
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| Length: | 395 |
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| Molecular Weight: | 43597.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MTDRQTDTAP SPSYHLLPGR RRTVDAAASR GQGPEPAPGG GVEGVGARGV ALKLFVQLLG
61: CSRFGGAVVR AGEAEPSGAA RSASSGREEP QPEEGEEEEE KEEERGPQWR LGARKPGSWT
121: GEAAVCADSA PAARAPQALA RASGRGGRVA RRGAEESGPP HSPSRRGSAS RAGPGRASET
181: MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD
241: IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM
301: SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVPCGPC SERRKHLFVQ
361: DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR