8.A.35.1.5
Protein MmpS3 or LamA (Loss of asymmetry mutant A) of 299 aas with one very hydrophobic TMS at ~ residue 110. This protein is a component (subunit) of the complex involved in cell wall synthesis at the old pole. It is a mycobacterial divisome factor that when its gene is deleted, it collapses single-cell phenotypic heterogeneity (Rego et al. 2017). It coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria (Gupta et al. 2022).
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| Accession Number: | CCE37669 |
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| Protein Name: | CCE37669.1 mmpS3 [Mycobacterium tuberculosis UT205] |
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| Length: | 300 |
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| Molecular Weight: | |
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| Species: | Mycobacterium tuberculosis UT205 [1097669] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MSGPNPPGRE PDEPESEPVS DTGDERASGN HLPPVAGGGD KLPSDQTGET DAYSRAYSAP
61: ESEHVTGGPY VPADLRLYDY DDYEESSDLD DELAAPRWPW VVGVAAIIAA VALVVSVSLL
121: VTRPHTSKLA TGDTTSSAPP VQDEITTTKP APPPPPPAPP PTTEIPTATE TQTVTVTPPP
181: PPPPATTTAP PPATTTTAAA PPPTTTTPTG PRQVTYSVTG TKAPGDIISV TYVDAAGRRR
241: TQHNVYIPWS MTVTPISQSD VGSVEASSLF RVSKLNCSIT TSDGTVLSSN SNDGPQTSC