TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.35.1.1









MmpS4 protein

Bacteria
Actinomycetota
MmpS4 of Mycobacterium smegmatis (A0QPN7)
8.A.35.1.2









MmpS5 auxillary protein; functions with MmpL5 in the export of siderophores (Wells et al. 2013) and various drugs. Upregulation gives rise to antibiotic resistance (Briffotaux et al. 2017).

Bacteria
Actinomycetota
MmpS5 of Mycobacterium tuberculosis
8.A.35.1.3









Uncharacterized protein of 180 aas and 1 TMS.

Bacteria
Actinomycetota
UP of Rhodococcus wratislaviensis
8.A.35.1.4









Uncharacterized protein of 161 aas and 1 TMS.

Bacteria
Actinomycetota
UP of Amycolatopsis decaplanina
8.A.35.1.5









Protein MmpS3 or LamA (Loss of asymmetry mutant A) of 299 aas with one very hydrophobic TMS at ~ residue 110. This protein is a component (subunit) of the complex involved in cell wall synthesis at the old pole. It is a mycobacterial divisome factor that when its gene is deleted, it collapses single-cell phenotypic heterogeneity (Rego et al. 2017). It coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria (Gupta et al. 2022).

 

Bacteria
Actinomycetota
LamA of Mycobacterium tuberculosis