TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
8.A.35.1.1 | MmpS4 protein | Bacteria |
Actinomycetota | MmpS4 of Mycobacterium smegmatis (A0QPN7) |
8.A.35.1.2 | MmpS5 auxillary protein; functions with MmpL5 in the export of siderophores (Wells et al. 2013) and various drugs. Upregulation gives rise to antibiotic resistance (Briffotaux et al. 2017). | Bacteria |
Actinomycetota | MmpS5 of Mycobacterium tuberculosis |
8.A.35.1.3 | Uncharacterized protein of 180 aas and 1 TMS. | Bacteria |
Actinomycetota | UP of Rhodococcus wratislaviensis |
8.A.35.1.4 | Uncharacterized protein of 161 aas and 1 TMS. | Bacteria |
Actinomycetota | UP of Amycolatopsis decaplanina |
8.A.35.1.5 | Protein MmpS3 or LamA (Loss of asymmetry mutant A) of 299 aas with one very hydrophobic TMS at ~ residue 110. This protein is a component (subunit) of the complex involved in cell wall synthesis at the old pole. It is a mycobacterial divisome factor that when its gene is deleted, it collapses single-cell phenotypic heterogeneity (Rego et al. 2017). It coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria (Gupta et al. 2022).
| Bacteria |
Actinomycetota | LamA of Mycobacterium tuberculosis |