TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.69.1.1









BH3-only protein, also called Bcl-2-like protein 11, Bim, of 198 aas and 1 C-terminal TMS; induces apoptosis and anoikis (Fukazawa et al. 2004). Different isoforms have differing activities (Marani et al. 2002). Isoform Bim-alpha3 induces apoptosis, possibly through a caspase-mediated pathway, but isoforms BimAC and BimABC lack the ability to induce apoptosis.

Eukaryota
Metazoa, Chordata
Bim of Homo sapiens
8.A.69.1.2









Bcl-2 interacting mediator of cell death of 176 aas and one C-terminal TMS.

Eukaryota
Metazoa, Chordata
Bim of Danio rerio (Zebrafish) (Brachydanio rerio)
8.A.69.1.3









Bcl-2-like protein 11 of 166 aas and 1 C-terminal TMS

Eukaryota
Metazoa, Chordata
Bcl-2-like protein of Callorhinchus milii (Ghost shark)