| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.69.1.1 | BH3-only protein, also called Bcl-2-like protein 11, Bim, of 198 aas and 1 C-terminal TMS; induces apoptosis and anoikis (Fukazawa et al. 2004). Different isoforms have differing activities (Marani et al. 2002). Isoform Bim-alpha3 induces apoptosis, possibly through a caspase-mediated pathway, but isoforms BimAC and BimABC lack the ability to induce apoptosis. | Eukaryota |
Metazoa | Bim of Homo sapiens |
|
8.A.69.1.2 | Bcl-2 interacting mediator of cell death of 176 aas and one C-terminal TMS. | Eukaryota |
Metazoa | Bim of Danio rerio (Zebrafish) (Brachydanio rerio) |
|
8.A.69.1.3 | Bcl-2-like protein 11 of 166 aas and 1 C-terminal TMS | Eukaryota |
Metazoa | Bcl-2-like protein of Callorhinchus milii (Ghost shark) |