TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.90.1.1









Uroplakin 2, UPK2, of 184 aas and 2 or 3 TMSs, 1 or 2 N-terminal and 1 C-terminal.  UPK2 is a component of the asymmetric unit membrane (AUM), a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play a role in regulating the assembly of the AUM which regulates channel activities (see 8.A.40.1.1) (Chicote et al. 2017).

Eukaryota
Metazoa, Chordata
UPK2 of Homo sapiens
8.A.90.1.2









UPK2 of 179 aas and 1 - 3 TMSs, possibly 0, 1 or 2 TMSs N-terminal and 1 C-terminal.

Eukaryota
Metazoa, Chordata
UPK2 of Salmo salar (Atlantic salmon)
8.A.90.1.3









UPK2 of 188 aas and 2 TMSs, one N-terminal and one C-terminal

Eukaryota
Metazoa, Chordata
UPK2 of Lepisosteus oculatus (Spotted gar)
8.A.90.2.1









Uroplakin 3a (UKP3a) of 287 aas and 2 probable TMSs, one N-terminal and one C-terminal (Chicote et al. 2017).

Eukaryota
Metazoa, Chordata
UKP3a of Homo sapiens
8.A.90.2.2









Uroplakin 3b, UPK3B, of 320 aas

Eukaryota
Metazoa, Chordata
UPK3b of Homo sapiens
8.A.90.2.3









Uroplakin 3c, UPK3C, of 263 aas and 2 TMSs, one N-terminal and one C-terminal.

Eukaryota
Metazoa, Chordata
UPK3c of Homo sapiens