8.B.14.2.5
Vitronectin, VTN, of 478 aas. Vitronectin is a cell adhesion and spreading
factor found in serum and tissues. It interacts with
glycosaminoglycans and proteoglycans. It is recognized by certain members
of the integrin family and serves as a cell-to-substrate adhesion
molecule. It is also an inhibitor of the membrane-damaging effect of the terminal
cytolytic complement pathway. It captures and clears soluble precursors of the membrane attack complex (sMAC) (Menny et al. 2021).
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| Accession Number: | P04004 |
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| Protein Name: | Vitronectin |
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| Length: | 478 |
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| Molecular Weight: | 54306.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Parasitophorous vacuole1 |
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| Substrate |
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1: MAPLRPLLIL ALLAWVALAD QESCKGRCTE GFNVDKKCQC DELCSYYQSC CTDYTAECKP
61: QVTRGDVFTM PEDEYTVYDD GEEKNNATVH EQVGGPSLTS DLQAQSKGNP EQTPVLKPEE
121: EAPAPEVGAS KPEGIDSRPE TLHPGRPQPP AEEELCSGKP FDAFTDLKNG SLFAFRGQYC
181: YELDEKAVRP GYPKLIRDVW GIEGPIDAAF TRINCQGKTY LFKGSQYWRF EDGVLDPDYP
241: RNISDGFDGI PDNVDAALAL PAHSYSGRER VYFFKGKQYW EYQFQHQPSQ EECEGSSLSA
301: VFEHFAMMQR DSWEDIFELL FWGRTSAGTR QPQFISRDWH GVPGQVDAAM AGRIYISGMA
361: PRPSLAKKQR FRHRNRKGYR SQRGHSRGRN QNSRRPSRAT WLSLFSSEES NLGANNYDDY
421: RMDWLVPATC EPIQSVFFFS GDKYYRVNLR TRRVDTVDPP YPRSIAQYWL GCPAPGHL