| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
9.A.46.1.1 | Tetraspanning Clarin-1, CLRN1 (USH3A gene). The causative protein which when mutated, gives rise to human Usher syndrome type 3A (Phillips et al. 2013), blind-deafness (Reiners et al. 2006). It exists in the USH complex involved in mechano-transduction in auditory hair cells and phooreceptors (Zallocchi et al. 2009; Ogun and Zallocchi 2014). | Eukaryota |
Metazoa, Chordata | Clarin-1 of Homo sapiens (P58418) |
|
9.A.46.1.2 | Tetraspanning Clarin-2 | Eukaryota |
Metazoa, Chordata | Clarin-2 of Homo sapiens (A0PK11) |
|
9.A.46.1.3 | Tetraspanning Clarin-3 | Eukaryota |
Metazoa, Chordata | Clarin-3 of Homo sapiens (Q8NCR9) |
|
9.A.46.1.4 | Clarin-1 (Clrn1) of 232 aas and 4 TMSs. Present in hair cells and photreceptors where it's defect causes hearing and visual loss (Usher syndrome type 3 in humans) (Ogun and Zallocchi 2014). | Eukaryota |
Metazoa, Chordata | Clarin-1 of Danio rerio (Zebrafish) (Brachydanio rerio) |
|
9.A.46.2.1 | Sea anemone clarin homologue | Eukaryota |
Metazoa, Cnidaria | Clarin homologue of Nematostella vectensis (A7SGP9) |
|
9.A.46.2.2 | Uncharacterized protein of 224 aas and 4 TMSs. | Eukaryota |
Metazoa, Nematoda | UP of Necator americanus (Human hookworm) |
|
9.A.46.2.3 | Fly clarin homologue, CG1103 isoform A | Eukaryota |
Metazoa, Arthropoda | Clarin homologue of Drosophila melanogaster (Q960K3) |
|
9.A.46.2.4 | Uncharacterized protein of 225 aas and 4 TMSs | Eukaryota |
Metazoa, Arthropoda | UP of Acyrthosiphon pisum (Pea aphid) |
|
9.A.46.2.5 | Uncharacterized protein of 236 aas and 4 TMSs. | Eukaryota |
Metazoa, Mollusca | UP of Lottia gigantea (Giant owl limpet) |