9.B.18.2.4
dTDP-glucose 4,6-dehydratase 2, RffG, of 355 aas and possibly one N-terminal TMS. It catalyzes the dehydration of dTDP-D-glucose to form
dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving
oxidation, dehydration and reduction (Hegeman et al. 2001). RffG increases the survival rate after exposure of E. coli to acid stress by 4500 times (Yang et al. 2022).
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| Accession Number: | P27830 |
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| Protein Name: | dTDP-glucose 4,6-dehydratase 2 |
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| Length: | 355 |
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| Molecular Weight: | 39754.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MRKILITGGA GFIGSALVRY IINETSDAVV VVDKLTYAGN LMSLAPVAQS ERFAFEKVDI
61: CDRAELARVF TEHQPDCVMH LAAESHVDRS IDGPAAFIET NIVGTYTLLE AARAYWNALT
121: EDKKSAFRFH HISTDEVYGD LHSTDDFFTE TTPYAPSSPY SASKASSDHL VRAWLRTYGL
181: PTLITNCSNN YGPYHFPEKL IPLMILNALA GKSLPVYGNG QQIRDWLYVE DHARALYCVA
241: TTGKVGETYN IGGHNERKNL DVVETICELL EELAPNKPHG VAHYRDLITF VADRPGHDLR
301: YAIDASKIAR ELGWLPQETF ESGMRKTVQW YLANESWWKQ VQDGSYQGER LGLKG