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9.B.418.1.1
Insulin-induced gene 2 protein, INSIG2, of 225 aas and 6 TMSs. It functions with SCAP (TC# 2.A.6.6.4) to control the  of enzymes and transport systems involved in the biosynthesis of cholesterol and other sterols (Yan et al. 2021). See family description for details.

Accession Number:Q9Y5U4
Protein Name:Insulin-induced gene 2 protein
Length:225
Molecular Weight:24778.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MAEGETESPG PKKCGPYISS VTSQSVNLMI RGVVLFFIGV FLALVLNLLQ IQRNVTLFPP 
61:	DVIASIFSSA WWVPPCCGTA SAVIGLLYPC IDRHLGEPHK FKREWSSVMR CVAVFVGINH 
121:	ASAKVDFDNN IQLSLTLAAL SIGLWWTFDR SRSGFGLGVG IAFLATVVTQ LLVYNGVYQY 
181:	TSPDFLYVRS WLPCIFFAGG ITMGNIGRQL AMYECKVIAE KSHQE