Bcl-2 Superfamily

The Bcl-2 Superfamily includes two families in TCDB, the Bcl-2 family (TC# 1.A.21), consisting of homologues, some of which form transmembrane pores, and the Bim Family (8.A.69), members of which influence apoptosis, either positively or negatively, and interact with TOM complex proteins (TC# 3.A.8).