9.B.144 The DUF3367 (DUF3367) Family This family, of unknown function, consists of large proteins of greater than 500 aas with more than 12 TMSs. The family is of relatively moderate size, having representation in a limited number of bacterial and archaeal phyla. It may be a family of glycosyltransferases related to the known glycosyl transferase of family 9.B.142, but it may also be a family of peptidases related to 9.B.252.3.
This family belongs to the Glycosyl/Acyl Transferase (GAT) Superfamily.
References:
Pinilla, C.M.B., P. Stincone, and A. Brandelli. (2021). Proteomic analysis reveals differential responses of Listeria monocytogenes to free and nanoencapsulated nisin. Int J Food Microbiol 346: 109170. [Epub: Ahead of Print]
Examples:
TC#	Name	Organismal Type	Example
9.B.144.1.1	Hypothetical protein of 834 aas and 14 putative TMSs in a 1 + 6 + 6 + 1 arrangement.	Planctomycetes	HP of Rhodopirellula baltica

9.B.144.1.2	Hypothetical protein of 934 aas and 15 putative TMSs in a 14 + 1 arrangement.	Chloroflexi	HP of Caldillinea aerophilia

9.B.144.1.3	Hypothetical protein of 811 aas and 14 TMSs in a 1 + 6 + 6 + 1 arrangement.	Proteobacteria	HP of Geobacter sulfurreducens

9.B.144.1.4	Hypothetical protein of 830 aas and 14 TMSs in a 1 + 6 + 6 + 1 arrangement.	Bacterioidetes	HP of Provotella saccharolytica

9.B.144.1.5	Uncharacterized protein of 859 aas and 14 TMSs in a 1 + 6 + 6 + 1 arrangement.	Firmicutes	UP of Streptococcus suis

9.B.144.1.6	Uncharacterized protein of 844 aas and 15 TMSs.		UP of Oenococcus oeni

9.B.144.1.7	Uncharacterized protein of 801 aas and 14 TMSs in a 1 + 6 + 6 +1 arrangement		UP of Nitrolancea hollandica

9.B.144.1.8	YfhO of 952 aas and 14 TMSs in a 1 (N-terminal) + 12 + 1 (C-terminal) TMS arrangement. YfhO is involved in glycosylation of cell wall teichoic acids and is induced in response to nisin (TC# 1.C.20.1.1) treatment (Pinilla et al. 2021).		YfhO of Listeria monocytogenes

Examples:
TC#	Name	Organismal Type	Example
9.B.144.2.1	Hypothetical protein of 736 aas and 10 - 14 TMSs.	Archaea	HP of Methanosarcina barkeri

9.B.144.2.2	Uncharacterized protein of 703 aas	Proteobacteria	UP of Desulfatibacillum alkenivorans

Examples:
TC#	Name	Organismal Type	Example
9.B.144.3.1	Uncharacterized protein of 646 aas and 17 TMSs.		UP of Methanosarcina horonobensis

9.B.144.3.2	Uncharacterized protein of 671 aas and 15 TMSs.		UP of Candidatus Daviesbacteria bacterium