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1.A.14.2.3
The 7 TMS proton-sensitive Ca2+ leak channel, YetJ.  The activity and high resolution 3-d structure have been determined (Chang et al. 2014).

Accession Number:O31539
Protein Name:Uncharacterized protein YetJ
Length:214
Molecular Weight:23829.00
Species:Bacillus subtilis [1423]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ca2+

Cross database links:

HEGENOM: HBG338613 HBG338613
Entrez Gene ID: 938782   
Pfam: PF01027   
KEGG: bsu:BSU07200    bsu:BSU07200   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (2)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
Structure:
4PGR   4PGS   4PGU   4PGV   4PGW   4TKQ     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQATVHESKQ SIMQRILTVF VFTLLIATVG LFIGQFVPVA LMLPLSILEV AMIILAFWMR 
61:	RRKAVGYAFV YTFAFVSGIT LFPIVSHYAS IAGAYVVLEA FGSTFVIFAV LGTIGAKMKK 
121:	DLSFLWSFLL VAVLALAVVG IFNIFSPLNS AAMMAYSVIG TIVFSLYILY DLNQIKHRHI 
181:	TEDLIPVMAL SLYLDFINLF INLLRFFGIL SSDD