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1.A.27.1.8
Phospholemman, FXYD1 or PLM of 92 aas and 1 TMS.  See 1.A.27.1.1 for details for the dog ortholog. Palmitoylation affects the regulation of cardiac electrophysiology, by modifying the sodium-calcium exchanger, phospholemman and the cardiac sodium pump, as well as the voltage-gated sodium channel (Essandoh et al. 2020). Palmitoylation of PLM inhibits the Na+ K+-ATPase while phosphorylation reverses this inhibition. The conserved FXYD motif is found in this protein at residues 29-32 (Cheung et al. 2013).

Accession Number:O00168
Protein Name:Phospholemman
Length:92
Molecular Weight:10441.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Single-pass type I membrane protein2
Substrate

Cross database links:

Structure:
2JO1     

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FASTA formatted sequence
1:	MASLGHILVF CVGLLTMAKA ESPKEHDPFT YDYQSLQIGG LVIAGILFIL GILIVLSRRC 
61:	RCKFNQQQRT GEPDEEEGTF RSSIRRLSTR RR