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1.A.59.1.1
The pore-forming peptide, Pep46 (derived from the structural polyprotein (PP) precursor (1012 aas) (Galloux et al. 2007). The 3-D NMR structure of Pep46 is known: Acc# 2IMUA (Galloux et al. 2010). 

Accession Number:P61825
Protein Name:Structural polyprotein
Length:1012
Molecular Weight:109671.00
Species:Avian infectious bursal disease virus (IBDV) [10995]
Location1 / Topology2 / Orientation3: Virion1
Substrate ions

Cross database links:

DIP: DIP-29594N
Pfam: PF01766    PF01767    PF01768   

Gene Ontology

GO:0030430 C:host cell cytoplasm
GO:0019028 C:viral capsid
GO:0008236 F:serine-type peptidase activity
GO:0005198 F:structural molecule activity

References (5)

[1] “Efficient rescue of infectious bursal disease virus from cloned cDNA: evidence for involvement of the 3'-terminal sequence in genome replication.”  Boot H.J.et.al.   10600604
[2] “Infectious bursal disease virus capsid protein VP3 interacts both with VP1, the RNA-dependent RNA polymerase, and with viral double-stranded RNA.”  Tacken M.G.et.al.   12388690
[3] “The 2.6-Angstrom structure of infectious bursal disease virus-derived T=1 particles reveals new stabilizing elements of the virus capsid.”  Garriga D.et.al.   16809295
[4] “Infectious bursal disease virus, a non-enveloped virus, possesses a capsid-associated peptide that deforms and perforates biological membranes.”  Galloux M.et.al.   17488723
[5] “Autoproteolytic activity derived from the infectious bursal disease virus capsid protein.”  Irigoyen N.et.al.   19144647
Structure:
2GSY   2IMU   3FBM     

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTNLQDQTQQ IVPFIRSLLM PTTGPASIPD DTLEKHTLRS ETSTYNLTVG DTGSGLIVFF 
61:	PGFPGSIVGA HYTLQSNGNY KFDQMLLTAQ NLPASYNYCR LVSRSLTVRS STLPGGVYAL 
121:	NGTINAVTFQ GSLSELTDVS YNGLMSATAN INDKIGNVLV GEGVTVLSLP TSYDLGYVRL 
181:	GDPIPAIGLD PKMVATCDSS DRPRVYTITA ADDYQFSSQY QPGGVTITLF SANIDAITSL 
241:	SVGGELVFQT SVHGLVLGAT IYLIGFDGTA VITRAVAANN GLTTGTDNLL PFNLVIPTNE 
301:	ITQPITSIKL EIVTSKSGGQ AGDQMSWSAR GSLAVTIHGG NYPGALRPVT LVAYERVATG 
361:	SVVTVAGVSN FELIPNPELA KNLVTEYGRF DPGAMNYTKL ILSERDRLGI KTVWPTREYT 
421:	DFREYFMEVA DLNSPLKIAG AFGFKDIIRA IRRIAVPVVS TLFPPAAPLA HAIGEGVDYL 
481:	LGDEAQAASG TARAASGKAR AASGRIRQLT LAADKGYEVV ANLFQVPQNP VVDGILASPG 
541:	VLRGAHNLDC VLREGATLFP VVITTVEDAM TPKALNSKMF AVIEGVREDL QPPSQRGSFI 
601:	RTLSGHRVYG YAPDGVLPLE TGRDYTVVPI DDVWDDSIML SKDPIPPIVG NSGNLAIAYM 
661:	DVFRPKVPIH VAMTGALNAC GEIEKVSFRS TKLATAHRLG LKLAGPGAFD VNTGPNWATF 
721:	IKRFPHNPRD WDRLPYLNLP YLPPNAGRQY HLAMAASEFK ETPELESAVR AMEAAANVDP 
781:	LFQSALSVFM WLEENGIVTD MANFALSDPN AHRMRNFLAN APQAGSKSQR AKYGTAGYGV 
841:	EARGPTPEEA QREKDTRISK KMETMGIYFA TPEWVALNGH RGPSPGQLKY WQNTREIPDP 
901:	NEDYLDYVHA EKSRLASEEQ ILRAATSIYG APGQAEPPQA FIDEVAKVYE INHGRGPNQE 
961:	QMKDLLLTAM EMKHRNPRRA LPKPKPKPNA PTQRPPGRLG RWIRTVSDED LE